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Research Department of Genetics Research Lines
University Medical Center Groningen

Research lines

   

Complex (multifactorial) diseases

Project leaders (PIs)

Sasha Zhernakova
Sebo Withoff
Vinod Kumar
Iris Jonkers

Cisca Wijmenga

Systems Genetics/Bioinformatics

  • Big data approaches to identifying environmental risk factors for disease
  • Factor analytic modeling of expression data and EQTL mapping
  • Using systems genetics to understand complex biological systems by integrating systems biology with genetics
  • Systems genetics of celiac disease, with a focus on non-coding regions of the genome
  • Integration of high-throughput expression and sequence data into the Oncology workstation (CTMM project)

See also the website of MOLGENIS

Morris Swertz
Lude Franke
Jingyuan Fu

5GPM: Five genes per minute

Whole-genome sequencing of critically ill newborns, more

Cleo van Diemen
Rolf Sijmons

Congenital diseases

Chromosome 6 research (a parent-driven project)
CHARGE syndrome
Phelan-McDermid syndrome (22q13 deletion syndrome)

EUROCAT - Epidemiological Surveillance of Congenital Anomalies
Eurolinkcat - establishing a linked European cohort of children with congenital anomalies

Dystrophic epidermolysis bullosa (DEB) (more in Dutch , in English )
Peter van de Akker

Oncogenetics

Clinical Genetics of Familial Cancer

Rolf Sijmons, Helga Westers, Klaas Kok

Renal Cell Cancer

Klaas Kok, Eva van den Berg

FaCD (Familial Cancer Database)

Rolf Sijmons

Neurogenetics

SpinoCerebellar Ataxia (SCA)

Genetic screening in children with epilepsy

Cardiogenetics

Mieke Kerstjens

ELSI (Ethics, legal, and social issues in clinical genetics)

The ELSI research programme aims to provide the evidence base for offering clinical genetic services to patients using new techniques and innovations more

Last modified:29 April 2024 11.26 a.m.