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Publicaties

EMA perspective on the value of model-informed drug development for labeling recommendations regarding medicine use during pregnancy and breastfeeding

Population Pharmacokinetic Modelling of Norepinephrine in Healthy Volunteers Prior to and During General Anesthesia

Target-controlled Infusion of Remimazolam in Healthy Volunteers Shows Some Acute Tolerance

A Joint Pharmacokinetic Model for the Simultaneous Description of Plasma and Whole Blood Tacrolimus Concentrations in Kidney and Lung Transplant Recipients

Development of a pharmacokinetic and pharmacodynamic model for intranasal administration of midazolam in older adults: a single-site two-period crossover study

Gentamicin Administration in Dialysis Patients: Before or After Hemodialysis?

Moving Toward a Question-Centric Approach for Regulatory Decision Making in the Context of Drug Assessment

Pharmacodynamic Effects of Norepinephrine in a Cross-Over Study with Awake and Anesthetized Healthy Volunteers

Pharmacodynamic mechanism-based interaction model for the haemodynamic effects of remifentanil and propofol in healthy volunteers

Development and evaluation of uncertainty quantifying machine learning models to predict piperacillin plasma concentrations in critically ill patients

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