I. Manfredonia, MSc

Faculteit Science and Engineering

Telefoon:

050 36 34468

E-mail:

i.manfredonia rug.nl

ORCID Research Portal

Research interests

PhD project: RNA secondary structures in the evolution of Flaviviruses

Thanks to their error-prone RNA polymerases, Flaviviruses exist in their hosts as genetically diversified populations of related genomes. In arthropod-borne flaviviruses (ssRNA+ viruses) which normally switch between arthropod and human hosts, the viral population is cyclically exposed to different and strong evolutionary forces. Among all the factors contributing to viral evolution, I’m interested in RNA secondary structures.

Publicaties

Genome-scale deconvolution of RNA structure ensembles

Morandi, E., Manfredonia, I., Simon, L. M., Anselmi, F., van Hemert, M. J., Oliviero, S. & Incarnato, D., feb.-2021, In: Nature Methods. 18, blz. 249-252 4 blz., s41592-021-01075-w.

Onderzoeksoutput › › peer review

RNA Post-Transcriptional Modification Mapping Data Analysis Using RNA Framework

Manfredonia, I. & Incarnato, D., 4-jun.-2021, RNA Modifications. Methods in Molecular Biology. McMahon, M. (uitgave). Springer, blz. 3-13 11 blz. (Methods in Molecular Biology; vol. 2298).

Onderzoeksoutput › › peer review

Structure and regulation of coronavirus genomes: State-of-the-art and novel insights from SARS-CoV-2 studies

Manfredonia, I. & Incarnato, D., mrt.-2021, In: Biochemical Society Transactions. 49, 1, blz. 341-352 12 blz., BST20200670.

Onderzoeksoutput › › peer review

Genome-wide mapping of SARS-CoV-2 RNA structures identifies therapeutically-relevant elements

Manfredonia, I., Nithin, C., Ponce-Salvatierra, A., Ghosh, P., Wirecki, T. K., Marinus, T., Ogando, N. S., Snijder, E. J., van Hemert, M. J., Bujnicki, J. M. & Incarnato, D., 16-dec.-2020, In: Nucleic Acids Research. 48, 22, blz. 12436-12452 17 blz.

Onderzoeksoutput › › peer review

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Alle (4) publicaties

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