Publications
In the list below, you find an overview of all publications of the department of Pharmaceutical Technology and Biopharmacy. Requests for electronic versions of publications may be submitted to respective corresponding authors.
2025
Dekkers,
B. G. J., Kerstjens, H. A. M., Breisnes, H. W.,
Leeming, D. J., Anthony, R. M., Frijlink, H. W.,
van der Werf, T. S., Kosterink, J. G. W.,
Alffenaar, J.-W. C., & Akkerman, O. W.
(2025). Azithromycin as host-directed therapy for pulmonary
tuberculosis - a randomized pilot trial. The
Journal of Infectious Diseases. Advance online
publication. https://doi.org/10.1093/infdis/jiaf069
van
der Koog, L., Woest, M., Gorter, I., Verschut,
V., Elferink, R., Zuidhof, A., Koloko Ngassie,
M. L., Bos, I. S. T., Dhakad, D.,
Wolters, J. C., Horvatovich, P., Prakash, Y.
S., Timens, W., Yildirim, A. O., Brandsma,
C.-A., Frijlink, H. W., Nagelkerke,
A., & Gosens, R. (Accepted/In press).
Fibroblast-derived osteoglycin promotes epithelial cell
repair. npj Regenerative Medicine,
10(16).
Jansen,
E. M., van der Koog, L., Elferink, R.,
Rafie, K., Nagelkerke, A., Gosens,
R., Frijlink, H. W., & Hinrichs,
W. (2025). Stabilized Extracellular Vesicle
Formulations for Inhalable Dry Powder Development.
Small. Advance online publication. https://doi.org/10.1002/smll.202411096
Akkerman-Nijland,
A. M., Hagedoorn, P., Rottier, B.
L., Grasmeijer, F., Frijlink, H. E.
W., van Luin, M., Ter Weijden, E., Merkus, P. J.,
Touw, D. J., Akkerman, O. W., &
Koppelman, G. H. (2025). Tolerability and
Pharmacokinetic Evaluation of Inhaled Dry Powder Tobramycin in
Children with Cystic Fibrosis.
Pharmaceutics, 17(3), Article 347.
https://doi.org/10.3390/pharmaceutics17030347
Visscher,
M., Frijlink, H. W., & Hinrichs, W.
L. J. (2025). What Is the Optimal Geometry of
Dissolving Microneedle Arrays? A Literature Review.
Pharmaceutics, 17(1), Article 124.
https://doi.org/10.3390/pharmaceutics17010124
Jurczak,
K. M., Zhang, R., Hinrichs, W. L. J.,
Grijpma, D. W., Schuurmann, R. C. L., de
Vries, J. P. P. M., & van Rijn, P. (2025).
Porous polytrimethylenecarbonate scaffolds: Design
considerations and porosity modulation techniques.
Materials and Design, 250, Article
113588. https://doi.org/10.1016/j.matdes.2025.113588
Kwiecień,
K., Knap, K., Heida, R., Czajkowski, J., Gorter, A.,
Ochońska, D., Mielczarek, P., Dorosz, A., Niewolik, D.,
Reczyńska-Kolman, K., Jaszcz, K., Brzychczy-Włoch, M.,
Sosnowski, T. R., Olinga, P., & Pamuła, E.
(2025). Novel copolymers of poly(sebacic anhydride) and
poly(ethylene glycol) as azithromycin carriers to the lungs.
Biocybernetics and Biomedical Engineering,
45(1), 114-136. https://doi.org/10.1016/j.bbe.2025.01.002
Karsten,
R. E. H., Gier, K., de Meijer, V.
E., Huibers, W. H. C., Permentier, H. P.,
Verpoorte, E., & Olinga, P. (2025).
Studying the intracellular bile acid concentration and
toxicity in drug-induced cholestasis: Comprehensive LC-MS/MS
analysis with human liver slices. Toxicology in
Vitro, 104, Article 106011. https://doi.org/10.1016/j.tiv.2025.106011
van
den Born-Bondt, T., Huizinga, H. P. S., Kappert, K. R., Westra, H.
H., van Zanten, J., Woerdenbag, H.
J., Maurer, J. M., & Gareb, B.
(2025). Development of an Adaptable Qualification Test Set
for Personnel Involved in Visual Inspection Procedures of
Parenteral Drug Products Manufactured Under Good Manufacturing
Practice Conditions in Hospital Pharmacy Compounding
Facilities. Pharmaceutics,
17(1), Article 74. https://doi.org/10.3390/pharmaceutics17010074
2024
Nguyen,
K. T. T., Zillen, D., Lasorsa,
A., van der Wel, P. C. A., Frijlink, H.
W., & Hinrichs, W. L. J. (2024).
Combinations of arginine and pullulan reveal the selective
effect of stabilization mechanisms on different lyophilized
proteins. International Journal of
Pharmaceutics, 654, Article 123938. https://doi.org/10.1016/j.ijpharm.2024.123938
Janssen,
P. H. M., Fathollahi, S., Dickhoff, B. H. J., &
Frijlink, H. W. (2024). Critical review on the role of
excipient properties in pharmaceutical powder-to-tablet continuous
manufacturing. Expert Opinion on Drug
Delivery, 21(7), 1069-1079. https://doi.org/10.1080/17425247.2024.2384698
Heida,
R., Jacob Silva, P. H., Akkerman, R.,
Moser, J., de Vries-Idema, J., Bornet, A.,
Pawar, S., Stellacci, F., Frijlink, H. W.,
Huckriede, A. L. W., & Hinrichs, W. L. J.
(2024). Inhibition of influenza virus infection in mice by
pulmonary administration of a spray dried antiviral.
European journal of pharmaceutics and biopharmaceutics :
official journal of Arbeitsgemeinschaft fur Pharmazeutische
Verfahrenstechnik e.V, 204, Article 114507. https://doi.org/10.1016/j.ejpb.2024.114507
Gosens,
R., van der Koog, L., Nagelkerke, A.
P., & Frijlink, H. W. (2024). Osteoglycin as regenerative agent for lung
tissue. (Patent No. WO2024258278).
de
Jong, L., Luinstra, M., Aalbers, A. F.,
Wijma-Vos, A. J., D’Angremont, E., van der Meulen, A. A. E.,
Rutgers, A. W. F., Steenhuis, L., Hagedoorn, P.,
van Laar, T., & Frijlink, H. W. (2024).
Therapeutic effect of an inhaled levodopa dry powder
formulation on off episodes in patients with Parkinson's
disease. Therapeutic advances in neurological
disorders, 17. https://doi.org/10.1177/17562864241289207
Putri,
K. S. S., Adhyatmika, A., Boorsma, C. E., Habibie,
H., Ruigrok, M. J. R., Heukels, P.,
Timens, W., de Jager, M. H., Hinrichs, W.
L. J., Olinga, P., & Melgert, B.
N. (2024). Osteoprotegerin is an Early Marker of the
Fibrotic Process and of Antifibrotic Treatment Responses in Ex Vivo
Lung Fibrosis. Lung, 202,
331–342. https://doi.org/10.1007/s00408-024-00691-5
Luo,
K., Geng, Y., Oosterhuis,
D., de Meijer, V. E., & Olinga,
P. (2024). Evaluating the antifibrotic potential of
naringenin, asiatic acid, and icariin using murine and human
precision-cut liver slices. Physiological
Reports, 12(21), Article e16136. https://doi.org/10.14814/phy2.16136
Biel,
C., Kastermans, A., Heidema, J., Pehrsson, M.,
Henstra, C., Mortensen, J., Faber, K. N.,
& Olinga, P. (2024). Fibrogenesis in Human Mucosa
and Muscularis Precision-Cut Intestinal Slices.
Cells, 13(13), Article 1084. https://doi.org/10.3390/cells13131084
Zhang,
Y., Sigaeva, A., Elías-Llumbet,
A., Fan, S., Woudstra, W.,
de Boer, R., Escobar, E.,
Reyes-San-Martin, C., Kisabacak, R., Oosterhuis,
D., Gorter, A. R., Coenen, B., Perona
Martinez, F. P., van den Bogaart, G.,
Olinga, P., & Schirhagl, R. (2024).
Free radical detection in precision-cut mouse liver slices
with diamond-based quantum sensing. Proceedings of
the National Academy of Sciences of the United States of
America, 121(43), Article e2317921121. https://doi.org/10.1073/pnas.2317921121
Biel,
C., Faber, K. N., Bank, R.
A., & Olinga, P. (2024). Matrix
metalloproteinases in intestinal fibrosis. Journal
of Crohn's and Colitis, 18(3), 462-478. https://doi.org/10.1093/ecco-jcc/jjad178
Li,
M., Larsen, F. T., van den Heuvel, M. C.,
Gier, K., Gorter, A. R., Oosterhuis, D.,
Bijzet, J., de Meijer, V. E., Ravnskjaer,
K., Nagelkerke, A., & Olinga, P.
(2024). Metabolic Dysfunction-Associated Steatotic Liver
Disease in a Dish: Human Precision-Cut Liver Slices as a Platform
for Drug Screening and Interventions.
Nutrients, 16(5), Article 626. https://doi.org/10.3390/nu16050626
Kiyuna,
L. A., Krishnamurthy, K. A., Homan, E.
B., Langelaar-Makkinje, M., Gerding,
A., Bos, T., Oosterhuis, D.,
Overduin, R. J., Schreuder, A. B., de
Meijer, V. E., Olinga, P., Derks, T. G.
J., van Eunen, K., Bakker, B.
M., & Oosterveer, M. H. (2024).
Precision-cut liver slices as an ex vivo model to assess
impaired hepatic glucose production.
Communications biology, 7, Article
1479. https://doi.org/10.1038/s42003-024-07070-z
Karsten,
R. E. H., Gier, K., Mulder, J.-P. S.
H., Grajewski, M., Olinga,
P., & Verpoorte, E. (2024). Real-Time
Monitoring of Oxygen-Consumption Rate in Mouse Liver Slices
Incubated in Organ-on-a-Chip Devices. Analytical
Chemistry, 96, 15871-15879. https://doi.org/10.1021/acs.analchem.4c00355
van
Leeuwen, L. L., Ruigrok, M. J. R., Kessler, B.
M., Leuvenink, H. G. D., & Olinga, P.
(2024). Targeted delivery of galunisertib using machine
perfusion reduces fibrogenesis in an integrated ex vivo renal
transplant and fibrogenesis model. British Journal
of Pharmacology, 181(3), 464-479. https://doi.org/10.1111/bph.16220
Glättli,
S. C., Elzinga, F. A., van der Bijl, W.,
Leuvenink, H. G. D., Prins, J. R., van
Goor, H., Gordijn, S. J., Olinga,
P., Touw, D. J., & Mian, P.
(2024). Variability in perfusion conditions and set-up
parameters used in ex vivo human placenta models: A literature
review. Placenta, 157, 37-49.
https://doi.org/10.1016/j.placenta.2024.03.007
Ekhart,
C., Wiarda, S. H. P., van de Koppel, S., Skalli, S., Alghamdi, W.,
Menniti-Ippolito, F., Tangchitkhachon, K., Mponda, J. S.,
Woerdenbag, H. J., & van Hunsel, F. (2025).
Qualitative Interviews with Stakeholders in Herbal
Pharmacovigilance and Recommendations for Best Practices to be
Applied Worldwide. Drug Safety,
48, 75-86. https://doi.org/10.1007/s40264-024-01480-y
Woerdenbag,
H. J., Ursidae, M., Ekhart, C., Schmidt, M.,
Vitalone, A., & van Hunsel, F. P. A. M. (2024).
Analysis of Adverse Reactions Associated with the Use of
Crataegus-Containing Herbal Products.
Pharmaceuticals, 17(11), Article
1490. https://doi.org/10.3390/ph17111490
Boersma,
H. H., Woerdenbag, M. M., Mulder, S., Poiesz,
T. W. T., Bekhof, L. B. S., Tholen, H. T., Luurtsema,
G., Lub-de Hooge, M. N., Giesen,
D., & Woerdenbag, H. J. (2024).
Comprehensive Analysis of Environmental Monitoring Data from
the Department of Nuclear Medicine and Molecular Imaging (NMMI) of
the University Medical Center Groningen (UMCG).
Hygiene, 4(3), 282-296. https://doi.org/10.3390/hygiene4030023
Copinga,
M. L., Kok, E. A., van Dam, A. J. J., Wever, A., Tromp,
A., & Woerdenbag, H. J. (2024). Developing
Medication Reviews to Improve the Aruban Healthcare System: A
Mixed-Methods Pilot Study. Pharmacy (Basel,
Switzerland), 12(4), Article 108. https://doi.org/10.3390/pharmacy12040108
Knol,
C. W. J., Stob, P. H., & Woerdenbag, H. J. (2024).
Development and Implementation of an Ultraviolet-Dye-Based
Qualification Procedure for Hand Washing and Disinfection to
Improve Quality Assurance of Pharmacy Preparations and Compounding,
Especially in Cleanrooms: A Pilot Study. Pharmacy
(Basel, Switzerland), 12(3), Article 73. https://doi.org/10.3390/pharmacy12030073
Dontje,
A. E. W. K., Schuiling-Veninga, C. C. M., van
Hunsel, F. P. A. M., Ekhart, C., Demirci, F., &
Woerdenbag, H. J. (2024). The Therapeutic Potential of
Essential Oils in Managing Inflammatory Skin Conditions: A Scoping
Review. Pharmaceuticals,
17(5), Article 571. https://doi.org/10.3390/ph17050571
2023
Otten,
A. T., van der Meulen, H. H., Steenhuis, M., Loeff, F.
C., Touw, D. J., Kosterink, J. G.
W., Frijlink, H. W., Rispens, T.,
Dijkstra, G., Visschedijk, M. C., &
Bourgonje, A. R. (2024). Clinical Validation of a
Capillary Blood Home-Based Self-Sampling Technique for Monitoring
of Infliximab, Vedolizumab, and C-Reactive Protein Concentrations
in Patients With Inflammatory Bowel Disease.
Inflammatory Bowel Diseases, 30(3),
325–335. https://doi.org/10.1093/ibd/izad103
van
der Kooij, R. S., Beukema, M., Huckriede,
A. L. W., Zuidema, J., Steendam, R., Frijlink, H.
W., & Hinrichs, W. L. J. (2023). A
Single Injection with Sustained-Release Microspheres and a
Prime-Boost Injection of Bovine Serum Albumin Elicit the Same IgG
Antibody Response in Mice.
Pharmaceutics, 15(2), Article 676.
https://doi.org/10.3390/pharmaceutics15020676
Frijlink,
H., Lagarce, F., Touw, D., &
Woerdenbag, H. (2023). Biopharmaceutics. In P.
Le Brun, S. Crauste-Manciet, I. Krämer, J. Smith, & H.
Woerdenbag (Eds.), Practical Pharmaceutics: An International
Guideline for the Preparation, Care and Use of Medicinal Products,
Second Edition (pp. 67-91). Springer International Publishing
AG. https://doi.org/10.1007/978-3-031-20298-8_5
Ahmed,
A. A., Otten, A. T., Gareb, B., Huijmans,
J. E., Eissens, A. C., Rehman, A., Dijkstra,
G., Kosterink, J. G. W., Frijlink, H.
W., & Schellekens, R. C. A. (2023). Capsules with
Ileocolonic-Targeted Release of Vitamin B2, B3, and C (ColoVit)
Intended for Optimization of Gut Health: Development and Validation
of the Production Process.
Pharmaceutics, 15(5), Article 1354.
https://doi.org/10.3390/pharmaceutics15051354
Nugrahadi,
P. P., Hinrichs, W. L. J., Frijlink, H.
W., Schöneich, C., & Avanti, C. (2023).
Designing Formulation Strategies for Enhanced Stability of
Therapeutic Peptides in Aqueous Solutions: A Review.
Pharmaceutics, 15(3), Article
15030935. https://doi.org/10.3390/pharmaceutics15030935
Heida,
R., Akkerman, R., Silva, P. H. J., Lakerveld,
A., Ortiz, D., Bigogno, C., Gasbarri, M., Van Kasteren, P. B.,
Stellacci, F., Frijlink, H. W., Huckriede,
A., & Hinrichs, W. (2023).
Development of an inhalable antiviral powder formulation
against respiratory syncytial virus. Journal of
Controlled Release, 357(5), 264-273. https://doi.org/10.1016/j.jconrel.2023.03.059
Otten,
A. T., Peters, V., Barth,
I., Stevens, C. L., Bourgonje, A.
R., Frijlink, H. W., Harmsen, H. J.
M., Rehman, A., Campmans-Kuijpers, M. J.
E., & Dijkstra, G. (2023). Effects of
ileocolonic delivered vitamin B2, B3 and C
(ColoVit) or the Groningen anti-inflammatory diet on disease course
and microbiome of patients with Crohn's disease (VITA-GrAID study):
a protocol for a randomised and partially blinded trial.
BMJ Open, 13(3), Article e069654. https://doi.org/10.1136/bmjopen-2022-069654
Heida,
R., Frijlink, H. W., & Hinrichs, W.
L. J. (2023). Inhalation of vaccines and antiviral
drugs to fight respiratory virus infections: Reasons to prioritize
the pulmonary route of administration.
mBio, 14(5), Article e0129523. https://doi.org/10.1128/mbio.01295-23
Mahri,
S., Wilms, T., Hagedorm, P., Guichard, M. J., Vanvarenberg, K.,
Dumoulin, M., Frijlink, H., & Vanbever, R. (2023).
Nebulization of PEGylated recombinant human deoxyribonuclease
I using vibrating membrane nebulizers: A technical feasibility
study. European Journal of Pharmaceutical
Sciences, 189, Article 106522. https://doi.org/10.1016/j.ejps.2023.106522
Frijlink,
H. W., Eissens, A. C., van Goor,
H., Mulder, D. J., & Joles, J. A. (2023).
Oral dosage forms of a therapeutically active
acid-labile salt and methods and uses related thereto.
(Patent No. WO2023140729).
Heida,
R., Hagedoorn, P., Van Meel, M. C., Prins, R.,
Simonis, F., Akkerman, R., Frijlink, H.
W., Huckriede, A., de Boer,
A., & Hinrichs, W. (2023).
Performance Testing of a Homemade Aerosol Generator for
Pulmonary Administration of Dry Powder Formulations to Mice.
Pharmaceutics, 15(7), Article 1847.
https://doi.org/10.3390/pharmaceutics15071847
Nguyen,
K. T. T., Zillen, D., van Heijningen, F. F. M.,
van Bommel, K. J. C., van Ee, R. J., Frijlink, H.
W., & Hinrichs, W. L. J. (2023).
Surface Engineering Methods for Powder Bed Printed Tablets to
Optimize External Smoothness and Facilitate the Application of
Different Coatings. Pharmaceutics,
15(9), Article 2193. https://doi.org/10.3390/pharmaceutics15092193
Lee,
J., Beukema, M., Zaplatynska, O. A., O'Mahony,
C., Hinrichs, W. L. J., Huckriede, A. L.
W., Bouwstra, J. A., & van der Maaden, K. (2023).
Efficient fabrication of thermo-stable dissolving microneedle
arrays for intradermal delivery of influenza whole inactivated
virus vaccine. Biomaterials Science,
11(20), 6790–6800. https://doi.org/10.1039/d3bm00377a
Hinrichs,
W., & van Gestel, R. (2023). Physical
Chemistry. In P. Le Brun, S. Crauste-Manciet, I.
Krämer, J. Smith, & H. Woerdenbag (Eds.), Practical
Pharmaceutics: An International Guideline for the Preparation, Care
and Use of Medicinal Products, Second Edition (2nd ed., pp.
93-125). Springer. https://doi.org/10.1007/978-3-031-20298-8_6
Bendixen,
S. M., Jakobsgaard, P. R., Hansen, D., Hejn, K. H., Terkelsen, M.
K., Bjerre, F. A., Thulesen, A. P., Eriksen, N. G., Hallenborg,
P., Geng, Y., Dam, T. V., Larsen, F. T., Wernberg, C.
W., Vijayathurai, J., Scott, E. A. H., Marcher, A. B., Detlefsen,
S., Grøntved, L., Dimke, H., ... Ravnskjaer, K. (2024).
Single cell-resolved study of advanced murine MASH reveals a
homeostatic pericyte signaling module. Journal of
Hepatology, 80(3), 467-481. https://doi.org/10.1016/j.jhep.2023.11.001
Geng,
Y., Arroyave-Ospina, J. C., Buist-Homan,
M., Plantinga, J., Olinga,
P., Reijngoud, D. J., Van Vilsteren, F.
G. I., Blokzijl, H., Kamps, J. A. A.
M., & Moshage, H. (2023).
Differential effects of oleate on vascular endothelial and
liver sinusoidal endothelial cells reveal its toxic features in
vitro. Journal of Nutritional
Biochemistry, 114, Article 109255. https://doi.org/10.1016/j.jnutbio.2022.109255
Li,
R., Vedelaar, T. A., Sigaeva,
A., Zhang, Y., Wu, K., Wang,
H., Wu, X., Olinga, P.,
Wlodarzyk-Biegun, M. K., & Schirhagl, R. (2023).
Fluorescent Nanodiamonds for Tracking Single Polymer
Particles in Cells and Tissues. Analytical
Chemistry, 95(35), 13046-13054. https://doi.org/10.1021/acs.analchem.3c01452
Geng,
Y., Wang, J., Serna-Salas, S.
A., Villanueva, A. H., Buist-Homan,
M., Arrese, M., Olinga, P., Blokzijl,
H., & Moshage, H. (2023). Hepatic
stellate cells induce an inflammatory phenotype in Kupffer cells
via the release of extracellular vesicles. Journal
of Cellular Physiology, 238(10), 2293-2303. https://doi.org/10.1002/jcp.31086
Luangmonkong,
T., Puphancharoensuk, P., Tongsongsang, V., Olinga,
P., & Parichatikanond, W. (2023). Hepatoprotective
Efficacy of Cycloastragenol Alleviated the Progression of Liver
Fibrosis in Carbon-Tetrachloride-Treated Mice.
Biomedicines, 11(1), Article 231. https://doi.org/10.3390/biomedicines11010231
Fridrichs,
J., Hamel, B., Kelder, W., van den Hoed, E., van den
Heuvel, M. C., Hulscher, J. B. F., &
Olinga, P. (2023). Human precision-cut cystic duct and
gallbladder slices: a novel method for studying
cholangiopathies. Frontiers in
Pediatrics, 11, Article 1058319. https://doi.org/10.3389/fped.2023.1058319
Moes,
C. A., Gan, C. T., Venema, L.
H., Hoffmann, R. F., Melgert, B.
N., Kerstjens, H. A. M., Olinga,
P., & Ruigrok, M. J. R. (2023).
Modelling Acid-Induced Lung Damage in Precision-Cut Lung
Slices: An Ex Vivo Animal Model.
Transplantology, 4(4), 185-196. https://doi.org/10.3390/transplantology4040018
Elzinga,
F. A., Khalili, B., Touw, D. J., Prins,
J. R., Olinga, P., Leuvenink, H. G.
D., van Goor, H., Gordijn, S.
J., Nagelkerke, A., & Mian, P.
(2023). Placenta-on-a-Chip as an In Vitro Approach to
Evaluate the Physiological and Structural Characteristics of the
Human Placental Barrier upon Drug Exposure: A Systematic
Review. Journal of Clinical Medicine,
12(13), Article 4315. https://doi.org/10.3390/jcm12134315
Woerdenbag,
H. J., Olinga, P., Kok, E. A., Brugman, D. A.
P., van Ark, U. F., Ramcharan, A. S., Lebbink, P. W.,
Hoogwater, F. J. H., Knapen, D. G., de
Groot, D. J. A., & Nijkamp, M. W. (2023).
Potential, Limitations and Risks of Cannabis-Derived Products
in Cancer Treatment. Cancers,
15(7), Article 2119. https://doi.org/10.3390/cancers15072119
de
Jong, I. E. M., Bodewes, S. B., van
Leeuwen, O. B., Oosterhuis, D., Lantinga,
V. A., Thorne, A. M., Lascaris,
B., van den Heuvel, M. C., Wells, R. G.,
Olinga, P., de Meijer, V. E., &
Porte, R. J. (2023). Restoration of Bile Duct Injury
of Donor Livers During Ex Situ Normothermic Machine
Perfusion. Transplantation,
107(6), e161-e172. https://doi.org/10.1097/TP.0000000000004531
van
Leeuwen, L. L., Ruigrok, M. J. R.,
Leuvenink, H. G. D., & Olinga, P. (2023).
Slice of Life: Porcine Kidney Slices for Testing Antifibrotic
Drugs in a Transplant Setting.
Transplantology, 4(2), 59-70. https://doi.org/10.3390/transplantology4020007
Jensen,
M. S., Merrild, C., Nørregaard, R., Olinga,
P., & Mutsaers, H. A. M. (2023).
Standardized Protocol for the Preparation of Precision-Cut
Kidney Slices: A Translational Model of Renal Fibrosis. In
T. D. Hewitson, N. D. Toussaint, & E. R. Smith (Eds.),
Methods in Molecular Biology (pp. 123-134). (Methods in
Molecular Biology; Vol. 2664). Humana Press. https://doi.org/10.1007/978-1-0716-3179-9_9
Luangmonkong,
T., Parichatikanond, W., & Olinga, P. (2023).
Targeting collagen homeostasis for the treatment of liver
fibrosis: Opportunities and challenges.
Biochemical Pharmacology, 215,
Article 115740. https://doi.org/10.1016/j.bcp.2023.115740
Simon,
E., Motyka, M., Prins, G. H., Li, M., Rust, W.,
Kauschke, S., Viollet, C., Olinga, P., &
Oldenburger, A. (2023). Transcriptomic profiling of induced
steatosis in human and mouse precision-cut liver slices.
Scientific Data, 10(1), Article 304.
https://doi.org/10.1038/s41597-023-02220-0
Tjeerdsma,
A. M., van Hunsel, F. P. A. M., van de Koppel, S.,
Ekhart, C., Vitalone, A., & Woerdenbag, H. J.
(2023). Analysis of Safety Concerns on Herbal Products with
Assumed Phytoestrogenic Activity.
Pharmaceuticals, 16(8), Article
1137. https://doi.org/10.3390/ph16081137
Woerdenbag,
H., Sznitowska, M., & Smeets, O. (2023). Basic
Operations. In P. Le Brun, S. Crauste-Manciet, I.
Krämer, J. Smith, & H. Woerdenbag (Eds.), Practical
Pharmaceutics: An International Guideline for the Preparation, Care
and Use of Medicinal Products, Second Edition (2nd ed., pp.
705-730). Springer. https://doi.org/10.1007/978-3-031-20298-8_29
Brun,
P. L., Crauste-Manciet, S., Krämer, I., Smith, J., &
Woerdenbag, H. (2023). Introduction. In P. Le
Brun, S. Crauste-Manciet, I. Krämer, J. Smith, & H.
Woerdenbag (Eds.), Practical Pharmaceutics: An International
Guideline for the Preparation, Care and Use of Medicinal Products,
Second Edition (pp. 1-5). Springer. https://doi.org/10.1007/978-3-031-20298-8_1
Le
Brun, P., Crauste-Manciet, S., Krämer, I., Smith, J.,
& Woerdenbag, H. (Eds.) (2023). Practical
Pharmaceutics: An International Guideline for the Preparation, Care
and Use of Medicinal Products, Second Edition. (2nd
ed.) Springer. https://doi.org/10.1007/978-3-031-20298-8
Le
Brun, P., Crauste-Manciet, S., Krämer, I., Smith, J.,
& Woerdenbag, H. (2023). Preface. In P. Le
Brun, S. Crauste-Manciet, I. Krämer, J. Smith, & H.
Woerdenbag (Eds.), Practical Pharmaceutics: An International
Guideline for the Preparation, Care and Use of Medicinal Products,
Second Edition (pp. v-vii). Springer International Publishing
AG.
Woerdenbag,
H., Visser, J. C., Kauss, T., & Sznitowska, M. (2023).
Rectal and Vaginal. In P. Le Brun , S.
Crauste-Manciet, I. Krämer, J. Smith, & H. Woerdenbag
(Eds.), Practical Pharmaceutics: An International Guideline for
the Preparation, Care and Use of Medicinal Products, Second
Edition (2nd ed., pp. 405-437). Springer. https://doi.org/10.1007/978-3-031-20298-8_19
Bekhof,
A. S. M. W., van Hunsel, F. P. A. M., van de Koppel,
S., & Woerdenbag, H. J. (2023). Safety
assessment and adverse drug reaction reporting of tea tree oil
(Melaleuca aetheroleum). Phytotherapy
Research, 37(4), 1309-1318. https://doi.org/10.1002/ptr.7687
2022
van
der Kooij, R. S., Steendam, R., Frijlink, H.
W., & Hinrichs, W. L. J. (2022). An
overview of the production methods for core-shell microspheres for
parenteral controlled drug delivery. European
journal of pharmaceutics and biopharmaceutics : official journal of
Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik
e.V, 170, 24-42. https://doi.org/10.1016/j.ejpb.2021.11.007
Jansen,
E. M., Frijlink, H. W., Hinrichs, W. L.
J., & Ruigrok, M. J. R. (2022). Are
inhaled mRNA vaccines safe and effective? A review of preclinical
studies. Expert Opinion on Drug
Delivery, 19(11), 1471-1485. https://doi.org/10.1080/17425247.2022.2131767
Heida,
R., Born, P. A., Tapia-Calle,
G., Frijlink, H. W., Salvati,
A., Huckriede, A. L. W., & Hinrichs,
W. L. J. (2022). Assessing the Immunomodulatory Effect
of Size on the Uptake and Immunogenicity of Influenza- and
Hepatitis B Subunit Vaccines In Vitro.
Pharmaceuticals, 15(7), Article 887.
https://doi.org/10.3390/ph15070887
Nguyen,
K. T. T., Heijningen, F. F. M., Zillen, D., van
Bommel, K. J. C., van Ee, R. J., Frijlink, H.
W., & Hinrichs, W. L. J. (2022).
Formulation of a 3D Printed Biopharmaceutical: The
Development of an Alkaline Phosphatase Containing Tablet with
Ileo-Colonic Release Profile to Treat Ulcerative Colitis.
Pharmaceutics, 14(10), Article 2179.
https://doi.org/10.3390/pharmaceutics14102179
Tian,
Y., Lee, J., van der Maaden, K., Bhide,
Y., de Vries-Idema, J. J., Akkerman,
R., O'Mahony, C., Jiskoot, W., Frijlink, H.
W., Huckriede, A. L. W., Hinrichs, W. L.
J., Bouwstra, J. A., & Beukema, M. (2022).
Intradermal Administration of Influenza Vaccine with
Trehalose and Pullulan-Based Dissolving Microneedle Arrays.
Journal of Pharmaceutical Sciences. https://doi.org/10.1016/j.xphs.2022.01.033
Woerdenbag,
H. J., Visser, J. C., Leferink Op Reinink, M.
P. A. M., van Orsoy, R. R., Eissens, A. C.,
Hagedoorn, P., Dijkstra, H., Allersma, D. P., Ng, S. W.,
Smeets, O. S. N. M., & Frijlink, H. W. (2022).
Performance of Tablet Splitters, Crushers, and Grinders in
Relation to Personalised Medication with Tablets.
Pharmaceutics, 14(2), Article 320.
https://doi.org/10.3390/pharmaceutics14020320
Ruigrok,
M. J. R., Roest, M. A. P., Frijlink, H.
W., Olinga, P., Hinrichs, W. L.
J., & Melgert, B. N. (2022). RANKL
confers protection against cell death in precision-cut lung
slices. Frontiers in Physiology,
13, Article 1029697. https://doi.org/10.3389/fphys.2022.1029697
de
Reus, Y. A., Hagedoorn, P., Sturkenboom,
M. G. G., Grasmeijer, F., Bolhuis, M.
S., Sibum, I., Kerstjens, H. A. M.,
Frijlink, H. W., & Akkerman, O. W. (2022).
Tolerability and pharmacokinetic evaluation of inhaled dry
powder hydroxychloroquine in healthy volunteers.
PLoS ONE, 17(8), Article e0272034.
https://doi.org/10.1371/journal.pone.0272034
Li,
M., de Meijer, V., Olinga,
P., Nagelkerke, A., & Geng, Y.
(2022). Development of an ex vivo model for non-alcoholic
fatty liver disease using precision-cut liver slices.
Journal of Hepatology, 77,
S711-S711.
Suriguga,
S., Li, M., Luangmonkong, T., Boersema,
M., de Jong, K. P., Oosterhuis,
D., Gorter, A. R., Beljaars, L., &
Olinga, P. (2022). Distinct responses between healthy
and cirrhotic human livers upon lipopolysaccharide challenge:
possible implications for acute-on-chronic liver failure.
American journal of physiology. Gastrointestinal and
liver physiology, 323(2), G114-G125. https://doi.org/10.1152/ajpgi.00243.2021
Luo,
K., Geng, Y., de Meijer, V.,
Oosterhuis, D., & Olinga, P. (2022).
Evaluation of the antifibrotic effects of naringenin, asiatic
acid and icariin by using precision-cut liver slices of mouse and
human. Journal of Hepatology,
77, S484-S484.
van
Furth, L. A., Leuvenink, H. G. D., Seras,
L., Graaf, I. A. M. D., Olinga, P.,
& Leeuwen, L. L. V. (2022). Exploring Porcine
Precision-Cut Kidney Slices as a Model for Transplant-Related
Ischemia-Reperfusion Injury.
Transplantology, 3(2),
139–151. https://doi.org/10.3390/transplantology3020015
Biel,
C., Martinec, O., Sibering, B., van Summeren, K.,
Wessels, A. M. A., Touw, D. J., de Jong,
K. P., de Meijer, V. E., Faber, K.
N., Klooster, J. P. T., de Graaf, I. A.
M., & Olinga, P. (2022). Extending
the viability of human precision-cut intestinal slice model for
drug metabolism studies. Archives of
toxicology. https://doi.org/10.1007/s00204-022-03295-1
Karsten,
R. E. H., Krijnen, N. J. W., Maho, W., Permentier,
H., Verpoorte, E., & Olinga,
P. (2022). Mouse precision-cut liver slices as an
ex vivo model to study drug-induced cholestasis.
Archives of toxicology, 96(9),
2523-2543. https://doi.org/10.1007/s00204-022-03321-2
Adhyatmika,
A., Putri, K. S. S., Gore, E., Mangnus, K. A., Reker-Smit,
C., Schuppan, D., Beljaars, L., Olinga,
P., & Melgert, B. N. (2022).
Osteoprotegerin Expression in Liver is Induced by IL13
through TGFβ. Cellular physiology and
biochemistry, 56(1), 28-38. https://doi.org/10.33594/000000492
van
Leeuwen, L., Leuvenink, H. G. D., Olinga,
P., & Ruigrok, M. (2022). Shifting
Paradigms for Suppressing Fibrosis in Kidney Transplants:
Supplementing Perfusion Solutions With Anti-fibrotic Drugs.
Frontiers in Medicine, 8, Article
806774. https://doi.org/10.3389/fmed.2021.806774
Kurniawan,
D. W., Booijink, R., Jajoriya, A. K., Dhawan, G., Mishra, D.,
Oosterhuis, D., Argemi, J., Storm, G., Olinga,
P., Bataller, R., Mohanty, S. K., Mishra, D. P., Prakash,
J., & Bansal, R. (2022). Src kinase as a potential
therapeutic target in non-alcoholic and alcoholic
steatohepatitis. Clinical and Translational
Discovery, 2(1), Article e18. https://doi.org/10.1002/ctd2.18
Puerta
Cavanzo, N., Riesmeijer, S. A.,
Holt-Kedde, I. L., Werker, P. M. N.,
Piersma, B., Olinga, P., & Bank, R.
A. (2022). Verteporfin ameliorates fibrotic aspects of
Dupuytren's disease nodular fibroblasts irrespective the activation
state of the cells. Scientific
Reports, 12(1), Article 13940. https://doi.org/10.1038/s41598-022-18116-9
van
Hunsel, F. P. A. M., van der Kooi, D., van de Koppel, S.,
Kroes, B. H., & Woerdenbag, H. J. (2022).
Analysis of Reports on Adverse Drug Reactions Related to
Herbal Medicinal Products and Herbal Supplements in the Netherlands
Received by the National Pharmacovigilance Centre Lareb.
Drug Safety, 45(6), 651-661. https://doi.org/10.1007/s40264-022-01180-5
Borgonje,
P. E., Wibier, L., Noordman, P., Woerdenbag, H.
J., & Gareb, B. (2022). The
Development and Implementation of Airflow Visualization Studies
("Smoke" Studies) as a Training Tool in Aseptic Hospital
Compounding Facilities. Pharmacy (Basel,
Switzerland), 10(5), Article 101. https://doi.org/10.3390/pharmacy10050101
2021
Heida,
R., Hinrichs, W. L. J., & Frijlink,
H. W. (2022). Inhaled vaccine delivery in the combat
against respiratory viruses: A 2021 overview of recent developments
and implications for COVID-19. Expert review of
vaccines, 21(7), 957-974. https://doi.org/10.1080/14760584.2021.1903878
Larmené-Beld,
K., Wijnsma, R., Kuiper, A., van Berkel, S., Robben, H.,
Taxis, K., & Frijlink, H. (2022).
Science- and risk-based strategy to qualify prefillable
autoclavable syringes as primary packaging material.
European Journal of Hospital Pharmacy: Science and
Practice, 29(5), 248-254. https://doi.org/10.1136/ejhpharm-2020-002333
Broesder,
A., Bircan, S. Y., De Waard, A. B., Eissens, A.
C., Frijlink, H. W., & Hinrichs, W.
L. J. (2021). Formulation and in vitro evaluation of
pellets containing sulfasalazine and caffeine to verify
ileo-colonic drug delivery.
Pharmaceutics, 13(12), Article 1985.
https://doi.org/10.3390/pharmaceutics13121985
Ruigrok,
M. J. R., Frijlink, H. W., Melgert, B.
N., Olinga, P., & Hinrichs, W. L.
J. (2021). Gene therapy strategies for idiopathic
pulmonary fibrosis: recent advances, current challenges, and future
directions. Molecular Therapy - Methods &
Clinical Development, 20, 483-496. https://doi.org/10.1016/j.omtm.2021.01.003
Broesder,
A., Berends, J. M. E., Scheepers, S. M.,
Nguyen, D. N., Frijlink, H. W., & Hinrichs,
W. L. J. (2021). Ileo-Colon Targeting of the Poorly
Water-Soluble Drug Celecoxib Using a pH-Dependent Coating in
Combination with Self-Emulsifying Drug Delivery or Solid Dispersion
Systems. Pharmaceutics,
13(5). https://doi.org/10.3390/pharmaceutics13050731
Gareb,
B., Beugeling, M., Posthumus, S., Otten,
A. T., Dijkstra, G., Kosterink, J. G.
W., & Frijlink, H. W. (2021).
Infliximab formulation strategy for a stable ileo-colonic
targeted oral dosage form intended for the topical treatment of
inflammatory bowel disease. Journal of drug
delivery science and technology, 64, Article
102552. https://doi.org/10.1016/j.jddst.2021.102552
van
der Kooij, R. S., Steendam, R., Zuidema, J., Frijlink,
H. W., & Hinrichs, W. L. J. (2021).
Microfluidic Production of Polymeric Core-Shell Microspheres
for the Delayed Pulsatile Release of Bovine Serum Albumin as a
Model Antigen. Pharmaceutics,
13(11), Article 1854. https://doi.org/10.3390/pharmaceutics13111854
Zillen,
D., Beugeling, M., Hinrichs, W. L.
J., Frijlink, H. W., & Grasmeijer,
F. (2021). Natural and bioinspired excipients for dry
powder inhalation formulations. Current Opinion in
Colloid and Interface Science, 56, Article
101497. https://doi.org/10.1016/j.cocis.2021.101497
Ruigrok,
M. J. R., El Amasi, K. E. M., Leeming, D. J., Sand, J. M.
B., Frijlink, H. W., Hinrichs, W. L.
J., & Olinga, P. (2021). Silencing
Heat Shock Protein 47 (HSP47) in Fibrogenic Precision-Cut Lung
Slices: A Surprising Lack of Effects on Fibrogenesis?
Frontiers in Medicine, 8, Article
607962. https://doi.org/10.3389/fmed.2021.607962
Sahal,
G., Woerdenbag, H. J., Hinrichs, W. L.
J., Visser, A., van der Mei, H.
C., & Bilkay, I. S. (2021). Candida Biofilm
Formation Assay on Essential Oil Coated Silicone Rubber.
Bio-Protocol, 11(5), Article 3941.
https://doi.org/10.21769/BioProtoc.3941
Setyaningsih,
D., Santoso, Y. A., Hartini, Y. S., Murti, Y. B., Hinrichs,
W. L. J., & Patramurti, C. (2021). Isocratic
high-performance liquid chromatography (HPLC) for simultaneous
quantification of curcumin and piperine in a microparticle
formulation containing Curcuma longa and Piper nigrum.
Heliyon, 7(3), Article e06541. https://doi.org/10.1016/j.heliyon.2021.e06541
Chakraborty,
P., Oosterhuis, D., Bonsignore, R., Casini,
A., Olinga, P., & Scheffers, D.-J.
(2021). An organogold compound as potential antimicrobial
agent against drug resistant bacteria: Initial mechanistic
insights. ChemMedChem,
16(19), 3060-3070. https://doi.org/10.1002/cmdc.202100342
van
Praagh, J. B., de Wit, J. G., Olinga,
P., de Haan, J. J., Nagengast, W.
B., Fehrmann, R. S. N., & Havenga,
K. (2021). Colorectal anastomotic leak: Transcriptomic
profile analysis. British Journal of
Surgery, 108(3), 326-333. https://doi.org/10.1093/bjs/znaa066
Geng,
Y., Buist-Homan, M., Olinga,
P., Blokzijl, H., & Moshage,
H. (2021). Conditioned medium of hepatic stellate
cells induces a pro-inflammatory phenotype in kupffer cells via the
release of extracellular vesicles.
Hepatology, 74, 808A-809A.
Mutsaers,
H. A. M., Nørregaard, R., & Olinga, P.
(2021). Editorial: Organ Fibrosis: Pathogenesis, Biomarkers
and Therapeutic Targets. Frontiers in
Medicine, 8, Article 793507. https://doi.org/10.3389/fmed.2021.793507
Pasmans,
K., Adriaens, M. E., Olinga, P., Langen, R., Rensen,
S. S., Schaap, F. G., Olde Damink, S. W. M., Caiment, F., van Loon,
L. J. C., Blaak, E. E., & Meex, R. C. R. (2021). Hepatic
Steatosis Contributes to the Development of Muscle Atrophy via
Inter-Organ Crosstalk. Frontiers in
endocrinology, 12, 733625. https://doi.org/10.3389/fendo.2021.733625
Li,
M., Oosterhuis, D., De Meijer, V.
E., Olinga, P., & Geng, Y.
(2021). High saccharides, fatty acids and insulin promote a
fibrogenic phenotype of healthy, but not nash, human precision-cut
liver slices. Hepatology, 74,
1069A-1069A.
Geng,
Y., Oosterhuis, D., De Meijer, V.
E., & Olinga, P. (2021). Lipids
inhibit the progression of fibrosis in human nash precision-cut
liver slices and human hepatic stellate cells.
Hepatology, 74, 1077A-1077A.
Jensen,
C. G., Jensen, M. S., Tingskov, S. J., Olinga, P.,
Nørregaard, R., & Mutsaers, H. A. M. (2021).
Local inhibition of indoleamine 2, 3-dioxygenase mitigates
renal fibrosis. Biomedicines,
9(8), Article 856. https://doi.org/10.3390/biomedicines9080856
Puerta
Cavanzo, N., Bigaeva, E., Boersema,
M., Olinga, P., & Bank, R. A.
(2021). Macromolecular Crowding as a Tool to Screen
Anti-fibrotic Drugs: The Scar-in-a-Jar System Revisited.
Frontiers in Medicine, 7, Article
615774. https://doi.org/10.3389/fmed.2020.615774
Bartucci,
R., van der Meer, A. Z., Boersma, Y. L., Olinga,
P., & Salvati, A. (2021).
Nanoparticle-induced inflammation and fibrosis in ex vivo
murine precision-cut liver slices and effects of nanoparticle
exposure conditions. Archives of
toxicology, 95, 1267–1285. https://doi.org/10.1007/s00204-021-02992-7
Karsten,
R. E. H., Grajewski, M., Mulder, J. P. S.
H., Olinga, P., & Verpoorte,
E. (2021). Real-Time, In-Line Monitoring of
Oxygen-Dependent Metabolism of Mouse Precision-Cut Liver Slices
Incubated in a Microfluidic Device. In MicroTAS 2021 -
25th International Conference on Miniaturized Systems for Chemistry
and Life Sciences (Vol. 1, pp. 503-504). (MicroTAS 2021 - 25th
International Conference on Miniaturized Systems for Chemistry and
Life Sciences). Chemical and Biological Microsystems Society
.
Martinec,
O., Biel, C., de Graaf, I. A. M.,
Huliciak, M., de Jong, K. P., Staud, F., Cecka,
F., Olinga, P., Vokral, I., & Cerveny, L. (2021).
Rifampicin Induces Gene, Protein, and Activity of
P-Glycoprotein (ABCB1) in Human Precision-Cut Intestinal
Slices. Frontiers in Pharmacology,
12, Article 684156. https://doi.org/10.3389/fphar.2021.684156
van
Furth, L., Maassen, H., Venema,
L., & Olinga, P. (2021). The effect
of the ketogenic diet on mitochondrial function in porcine
precision-cut kidney slices. Transplant
International, 34(S1), 273-274.
Prins,
G. H., Rios-Morales, M., Gerding,
A., Reijngoud, D.-J., Olinga,
P., & Bakker, B. M. (2021). The
Effects of Butyrate on Induced Metabolic-Associated Fatty Liver
Disease in Precision-Cut Liver Slices.
Nutrients, 13(12), Article 4203. https://doi.org/10.3390/nu13124203
Henstra,
C., van Praagh, J., Olinga, P., &
Nagelkerke, A. (2021). The gastrointestinal microbiota
in colorectal cancer cell migration and invasion.
Clinical & Experimental Metastasis,
38, 495–510. https://doi.org/10.1007/s10585-021-10130-x
Majorova,
D., Atkins, E., Martineau, H., Vokral, I., Oosterhuis,
D., Olinga, P., Wren, B., Cuccui, J., &
Werling, D. (2021). Use of Precision-Cut Tissue Slices as a
Translational Model to Study Host-Pathogen Interaction.
Frontiers in Veterinary Science, 8,
Article 686088. https://doi.org/10.3389/fvets.2021.686088
Herawati,
F., Yulia, R., Arifin, B., Frasetyo, I.,
Setiasih, Woerdenbag, H. J., Avanti, C., &
Andrajati, R. (2021). Educational Video Improves Knowledge
about Outpatients' Usage of Antibiotics in Two Public Hospitals in
Indonesia. Antibiotics ,
10(5), Article 606. https://doi.org/10.3390/antibiotics10050606
Mulder,
S. M. E., Jipping, A. M., Silvester, N., Van Hunsel, F. P. A.
M., Kroes, B. H., & Woerdenbag, H. J.
(2021). Gelijktijdig gebruik van zuclopentixol en
ayurvedische producten: Veilig of niet?
Pharmaceutisch Weekblad, 156(1-2),
31-36.
Zulzaga,
Z., Myagmarsuren, E., Woerdenbag, H. J., &
van Puijenbroek, E. P. (2021). Legislation and current
developments in adverse drug reaction reporting in Mongolia: how
far are we? Journal of Pharmaceutical Policy and
Practice, 14(1), Article 15. https://doi.org/10.1186/s40545-021-00298-8
2020
Heida,
R., Bhide, Y. C., Gasbarri, M., Kocabiyik,
Ö., Stellacci, F., Huckriede, A. L. W.,
Hinrichs, W. L. J., & Frijlink, H. W.
(2021). Advances in the development of entry inhibitors for
sialic-acid-targeting viruses. Drug Discovery
Today, 26(1), 122-137. https://doi.org/10.1016/j.drudis.2020.10.009
Akkerman-Nijland,
A. M., Akkerman, O. W., Grasmeijer,
F., Hagedoorn, P., Frijlink, H.
W., Rottier, B. L., Koppelman, G.
H., & Touw, D. J. (2021). The
pharmacokinetics of antibiotics in cystic fibrosis.
Expert Opinion on Drug Metabolism &
Toxicology, 17(1), 53-68. https://doi.org/10.1080/17425255.2021.1836157
Hagedoorn,
P., Bawary, W., Frijlink, H. W., &
Grasmeijer, F. (2020). A comparative analysis of
changes in pMDI drug dose delivery before and after detergent
coating using five antistatic valved holding chambers.
The Journal of Allergy and Clinical Immunology: In
Practice, 8(3), 1124-1125.e4. https://doi.org/10.1016/j.jaip.2019.09.021
Sibum,
I., Hagedoorn, P., Botterman, C. O.,
Frijlink, H. W., & Grasmeijer, F. (2020).
Automated Filling Equipment Allows Increase in the Maximum
Dose to Be Filled in the Cyclops(R)High Dose Dry Powder Inhalation
Device While Maintaining Dispersibility.
Pharmaceutics, 12(7), 1-14. Article
645. https://doi.org/10.3390/pharmaceutics12070645
Akkerman-Nijland,
A. M., Grasmeijer, F., Kerstjens, H. A.
M., Frijlink, H. W., van der Vaart,
H., Vonk, J. M., Hagedoorn,
P., Rottier, B. L., Koppelman, G.
H., & Akkerman, O. W. (2020).
Colistin dry powder inhalation with the Twincer (TM): An
effective and more patient friendly alternative to
nebulization. PLoS ONE,
15(9), Article e0239658. https://doi.org/10.1371/journal.pone.0239658
Hagedoorn,
P., Grasmeijer, F., Bawari, W., Frijlink,
H. W., & Grasmeijer, F. (2020).
Comparing five antistatic valved holding chambers: How
antistatic are they really? European Respiratory
Journal, 56. https://doi.org/10.1183/13993003.congress-2020.3177
Gareb,
B., Dijkstra, G., Kosterink, J. G.
W., & Frijlink, H. W. (2020). De
ontwikkeling van budesonidetabletten met nulde-orde-afgifte voor de
behandeling van ileo-colonische inflammatoire darmziekten en
vergelijking met huidige, commerciële preparaten.
Pharmaceutisch Weekblad, 155(6),
29-36. https://www.npfo.nl/artikel/de-ontwikkeling-van-budesonidetabletten-met-nulde-orde-afgifte-voor-de-behandeling-van-ileo
Tian,
Y., Bhide, Y. C., Woerdenbag, H.
J., Huckriede, A. L. W., Frijlink, H.
W., Hinrichs, W. L. J., & Visser, J.
C. (2020). Development of an Orodispersible Film
Containing Stabilized Influenza Vaccine.
Pharmaceutics, 12(3), Article 245.
https://doi.org/10.3390/pharmaceutics12030245
Weerts,
Z. Z. R. M., Masclee, A. A. M., Witteman, B. J. M., Clemens, C. H.
M., Winkens, B., Brouwers, J. R. B. J., Frijlink, H.
W., Muris, J. W. M., De Wit, N. J., Essers, B. A. B., Tack,
J., Snijkers, J. T. W., Bours, A. M. H., de Ruiter-van der Ploeg,
A. S., Jonkers, D. M. A. E., & Keszthelyi, D. (2020).
Efficacy and Safety of Peppermint Oil in a Randomized,
Double-Blind Trial of Patients With Irritable Bowel
Syndrome. Gastroenterology,
158(1), 123-136. Article 158. https://doi.org/10.1053/j.gastro.2019.08.026
Akkerman-Nijland,
A. M., Yousofi, M., Rottier, B. L., Van
der Vaart, H., Burgerhof, J. G. M.,
Frijlink, H. W., Touw, D. J., Koppelman,
G. H., & Akkerman, O. W. (2020).
Eradication of Pseudomonas aeruginosa in cystic fibrosis
patients with inhalation of dry powder tobramycin.
Therapeutic advances in respiratory disease,
14, Article 1753466620905279. https://doi.org/10.1177/1753466620905279
Pleguezuelos,
O., Dille, J., de Groen, S., Oftung, F.,
Niesters, H. G. M., Islam, M. A., Naess, L. M., Hungnes, O.,
Aldarij, N., Idema, D. L., Perez, A. F., James, E., Frijlink,
H. W., Stoloff, G., Groeneveld, P., & Hak,
E. (2020). Immunogenicity, Safety, and Efficacy of a
Standalone Universal Influenza Vaccine, FLU-v, in Healthy
Adults. Annals of Internal Medicine,
172(7), 453-462. https://doi.org/10.7326/M19-0735
Nguyen,
K. T. T., Frijlink, H. W., &
Hinrichs, W. L. J. (2020). Inhomogeneous Distribution
of Components in Solid Protein Pharmaceuticals: Origins,
Consequences, Analysis, and Resolutions. Journal
of Pharmaceutical Sciences, 109(1), 134-153.
https://doi.org/10.1016/j.xphs.2019.10.010
Ruigrok,
M., El-Amasi, K., Frijlink, H. W.,
Hinrichs, W., & Olinga, P. (2020).
Knockdown of heat shock protein 47 (HSP47) and its
effects on fibrogenesis. Poster session presented at
Keystone Symposia on Fibrosis and Tissue Repair, Victoria,
Canada.
Sibum,
I., Grasmeijer, F., Hagedoorn, P.,
& Frijlink, H. W. (2020). Optimisation of an
isoniazid dry powder formulation for pulmonary
administration. Journal of aerosol medicine and
pulmonary drug delivery, 33(2), A2-A2.
Broesder,
A., Woerdenbag, H. J., Prins, G.
H., Nguyen, D. N., Frijlink, H. W., &
Hinrichs, W. L. J. (2020). pH-dependent ileocolonic
drug delivery, part I: in vitro and clinical evaluation of novel
systems. Drug Discovery Today,
25(8), 1362-1373. https://doi.org/10.1016/j.drudis.2020.06.011
Broesder,
A., Kosta, A.-M. M. A. C., Woerdenbag, H.
J., Nguyen, D. N., Frijlink, H. W., &
Hinrichs, W. L. J. (2020). pH-dependent ileocolonic
drug delivery, part II: Preclinical evaluation of novel drugs and
novel excipients. Drug Discovery
Today, 25(8), 1374-1388. https://doi.org/10.1016/j.drudis.2020.06.012
Larmene-Beld,
K. H. M., van Berkel, S., Wijnsma, R., Taxis,
K., & Frijlink, H. W. (2020).
Prefilled Cyclic Olefin Sterilized Syringes of Norepinephrine
Injection Solution Do Not Need to Be Stabilized by
Antioxidants. Aaps pharmscitech,
21(7), 247. Article 247. https://doi.org/10.1208/s12249-020-01784-z
Hagedoorn,
P., Bawary, W., Frijlink, H. W., &
Grasmeijer, F. (2020). Relative lung dose from
antistatic valved holding chambers Reply. The
Journal of Allergy and Clinical Immunology: In
Practice, 8(3), 1166-1167. https://doi.org/10.1016/j.jaip.2019.11.023
Gareb,
B., Otten, A. T., Frijlink, H.
W., Dijkstra, G., & Kosterink, J. G.
W. (2020). Review: Local Tumor Necrosis Factor-alpha
Inhibition in Inflammatory Bowel Disease.
Pharmaceutics, 12(6), 1-31. Article
539. https://doi.org/10.3390/pharmaceutics12060539
Gerritsen,
J., Bloemers, J., van Rooij, K., de Leede, L., van der Geest,
R., Frijlink, H. W., Koppeschaar, H. P. F., Olivier,
B., & Tuiten, A. (2020). The Effect of Food on the
Pharmacokinetics of Buspirone After Single Administration of a
Sublingual Testosterone and Oral Buspirone Combination Tablet in
Healthy Female Subjects. Sexual
medicine, 8(2), 186-194. https://doi.org/10.1016/j.esxm.2020.01.005
Kocabiyik,
O., Cagno, V., Silva, P. J., Zhu, Y., Sedano, L., Bhide,
Y., Mettier, J., Medaglia, C., Da Costa, B., Constant, S.,
Huang, S., Kaiser, L., Hinrichs, W. L. J., Huckeriede,
A., Le Goffic, R., Tapparel, C., & Stellacci, F. (2021).
Non-Toxic Virucidal Macromolecules Show High Efficacy Against
Influenza Virus Ex Vivo and In Vivo. Advanced
science, 8(3), Article 2001012. https://doi.org/10.1002/advs.202001012
Smith-Cortinez,
N., Fagundes, R. R., Gomez, V., Kong,
D., de Waart, D. R., Heegsma, J., Sydor,
S., Olinga, P., de Meijer, V. E., Taylor,
C. T., Bank, R., Paulusma, C. C., & Faber,
K. N. (2021). Collagen release by human hepatic
stellate cells requires vitamin C and is efficiently blocked by
hydroxylase inhibition. The FASEB
Journal, 35(2), Article e21219. https://doi.org/10.1096/fj.202001564RR
Mortensen,
J. H., van Haaften, W. T., Karsdal, M. A., Bay-Jensen,
A.-C., Olinga, P., Grønbæk, H., Hvas, C. L.,
Manon-Jensen, T., Dijkstra, G., & Dige, A. (2021).
The Citrullinated and MMP-degraded Vimentin Biomarker (VICM)
Predicts Early Response to Anti-TNF alpha Treatment in Crohn's
Disease. Journal of clinical
gastroenterology, 55(1), 59-66. https://doi.org/10.1097/MCG.0000000000001341
Bartucci,
R., Paramanandana, A., Boersma, Y. L., Olinga,
P., & Salvati, A. (2020). Comparative
study of nanoparticle uptake and impact in murine lung, liver and
kidney tissue slices. Nanotoxicology,
14(6), 847-865. https://doi.org/10.1080/17435390.2020.1771785
Nomden,
M., Beljaars, L., Verkade, H.
J., Hulscher, J. B. F., & Olinga,
P. (2020). Current Concepts of Biliary Atresia and
Matrix Metalloproteinase-7: A Review of Literature.
Frontiers in Medicine, 7, Article
617261. https://doi.org/10.3389/fmed.2020.617261
van
Dijk, F., Hazelhoff, C. M., Post, E.,
Prins, G. G. H., Rombouts, K., Poelstra,
K., Olinga, P., & Beljaars, L.
(2020). Design of a Gene Panel to Expose the Versatile Role
of Hepatic Stellate Cells in Human Liver Fibrosis.
Pharmaceutics, 12(3), Article 278.
https://doi.org/10.3390/pharmaceutics12030278
Bigaeva,
E., Gore, E., Mutsaers, H. A. M.,
Oosterhuis, D., Kim, Y. O., Schuppan, D., Bank, R.
A., Boersema, M., & Olinga, P.
(2020). Exploring organ-specific features of fibrogenesis
using murine precision-cut tissue slices.
Biochimica et biophysica acta-Molecular basis of
disease, 1866(1), Article 165582. https://doi.org/10.1016/j.bbadis.2019.165582
Suriguga,
S., Luangmonkong, T., Mutsaers, H. A. M.,
Groothuis, G. M. M., & Olinga, P. (2020).
Host microbiota dictates the proinflammatory impact of LPS in
the murine liver. Toxicology in Vitro,
67, Article 104920. https://doi.org/10.1016/j.tiv.2020.104920
van
Haaften, W. T., Blokzijl, T., Hofker, H.
S., Olinga, P., Dijkstra,
G., Bank, R. A., & Boersema,
M. (2020). Intestinal stenosis in Crohn's disease
shows a generalized upregulation of genes involved in collagen
metabolism and recognition that could serve as novel anti-fibrotic
drug targets. Therapeutic advances in
gastroenterology, 13. https://doi.org/10.1177/1756284820952578
Gore,
E., Bigaeva, E., Oldenburger, A., Jansen, Y. J.
M., Schuppan, D., Boersema, M., Rippmann, J.
F., Broermann, A., & Olinga, P. (2020).
Investigating fibrosis and inflammation in an ex vivo NASH
murine model. American Journal of Physiology.
Gastrointestinal and Liver Physiology, 318(2),
G336-G351. https://doi.org/10.1152/ajpgi.00209.2019
Luangmonkong,
T., & Olinga, P. (2020). Modified culture
protocol for testing anti-fibrotic drugs using precision-cut liver
slices. Pharmaceutical Sciences Asia,
47(3), 301-309. https://doi.org/10.29090/psa.2020.03.019.0137
Iswandana,
R., Pham, B. T., Suriguga, S., Luangmonkong, T., van Wijk, L.
A., Jansen, Y. J. M., Oosterhuis, D.,
Maria Mutsaers, H. A., & Olinga, P. (2020).
Murine Precision-cut Intestinal Slices as a Potential
Screening Tool for Antifibrotic Drugs.
Inflammatory Bowel Diseases, 26(5),
678-686. https://doi.org/10.1093/ibd/izz329
Adhyatmika,
A., Beljaars, L., Putri, K. S. S., Habibie,
H., Boorsma, C. E., Reker-Smit, C.,
Luangmonkong, T., Guney, B., Haak, A., Mangnus, K. A., Post,
E., Poelstra, K., Ravnskjaer, K., Olinga,
P., & Melgert, B. N. (2020).
Osteoprotegerin Is more than a Possible Serum Marker in Liver
Fibrosis: A Study into Its Function in Human and Murine
Liver. Pharmaceutics, 12(5),
Article 471. https://doi.org/10.3390/pharmaceutics12050471
Prins,
G. H., & Olinga, P. (2020). Potential
implications of COVID-19 in non-alcoholic fatty liver
disease. Liver International,
40(10), 2568. https://doi.org/10.1111/liv.14484
Bigaeva,
E., Puerta Cavanzo, N., Stribos, E. G. D., de
Jong, A. J., Biel, C., Mutsaers, H. A.
M., Jensen, M. S., Nørregaard, R., Leliveld, A.
M., de Jong, I. J., Hillebrands,
J.-L., van Goor, H., Boersema,
M., Bank, R. A., & Olinga, P.
(2020). Predictive Value of Precision-Cut Kidney Slices as an
Ex Vivo Screening Platform for Therapeutics in Human Renal
Fibrosis. Pharmaceutics,
12(5), Article 459. https://doi.org/10.3390/pharmaceutics12050459
Habibie,
H., Song, S., Putri, K., Boorsma, C.,
Cool, R., Wu, X., Gosens,
R., Wang, Y., Quax, W.,
Olinga, P., Brandsma, C.-A., Timens,
W., Burgess, J., & Melgert, B.
(2020). RANKL contributes to lung tissue repair via promoting
type II epithelial cell proliferation. European
Respiratory Journal, 56. https://doi.org/10.1183/13993003.congress-2020.5029
van
Haaften, W. T., Mortensen, J. H., Dige, A. K., Gronbaek, H.,
Hvas, C. L., Bay-Jensen, A.-C., Karsdal, M. A., Olinga,
P., Manon-Jensen, T., & Dijkstra, G.
(2020). Serological Biomarkers of Tissue Turnover Identify
Responders to Anti-TNF Therapy in Crohn's Disease: A Pilot
Study. Clinical and translational
gastroenterology, 11(9), e00217. Article
00217. https://doi.org/10.14309/ctg.0000000000000217
Biel,
C., Bigaeva, E., Hesse, M., Bomers, J. J. M.,
van Summeren, K., Teunis, M. A. T., Vaessen, S., Ten Klooster, J.
P., & Olinga, P. (2020). Survival and
cellular heterogeneity of epithelium in cultured mouse and rat
precision-cut intestinal slices. Toxicology in
Vitro, 69, Article 104974. https://doi.org/10.1016/j.tiv.2020.104974
Bartucci,
R., Åberg, C., Melgert, B.
N., Boersma, Y. L., Olinga, P., &
Salvati, A. (2020). Time-Resolved Quantification of
Nanoparticle Uptake, Distribution, and Impact in Precision-Cut
Liver Slices. Small, 16(21),
Article e1906523. https://doi.org/10.1002/smll.201906523
Koster,
A. S., Mantel-Teeuwisse, A. K., Woerdenbag, H. J.,
Mulder, W. M. C., Wilffert, B., Schalekamp, T.,
Buurma, H., Wilting, I., & Westein, M. P. D. (2020).
Alignment of CanMEDS-Based Undergraduate and Postgraduate
Pharmacy Curricula in The Netherlands. Pharmacy
(Basel, Switzerland), 8(3), Article 117. https://doi.org/10.3390/pharmacy8030117
Visser,
J. C., Wibier, L., Kiefer, O., Orlu, M., Breitkreutz,
J., Woerdenbag, H. J., & Taxis, K.
(2020). A Pediatrics Utilization Study in The Netherlands to
Identify Active Pharmaceutical Ingredients Suitable for Inkjet
Printing on Orodispersible Films.
Pharmaceutics, 12(2), Article 164.
https://doi.org/10.3390/pharmaceutics12020164
Mulder,
S. M. E., Jipping, A.-M., Silvester, N., van Hunsel, F. P. A. M.,
Kroes, B. H., & Woerdenbag, H. J. (2020).
Gelijktijdig gebruik van zuclopentixol en ayurvedische
producten: Veilig of niet? Nederlands Platform
voor Farmaceutisch Onderzoek, (5), Article a1732.
Woerdenbag,
H., & Hak, E. (2020). Interview-based
cross-sectional needs assessment to advance the implementation of
an effective antibiotic stewardship program in Indonesian
hospitals. Health Policy OPEN,
1, Article 100002. https://doi.org/10.1016/j.hpopen.2019.100002
Visser,
J. C., Wibier, L., Mekhaeil, M., Woerdenbag, H.
J., & Taxis, K. (2020).
Orodispersible films as a personalized dosage form for
nursing home residents, an exploratory study.
International Journal of Clinical Pharmacy,
42(2), 436–444. https://doi.org/10.1007/s11096-020-00990-w
2019
Busscher,
H. J., Woudstra, W., van Kooten, T.
G., Jutte, P., Shi, L., Liu, J.,
Hinrichs, W. L. J., Frijlink, H. W., Shi, R.,
Liu, J., Parvizi, J., Kates, S., Rotello, V. M., Schaer, T. P.,
Williams, D., Grainger, D. W., & van der Mei, H.
C. (2020). Accepting higher morbidity in exchange for
sacrificing fewer animals in studies developing novel
infection-control strategies.
Biomaterials, 232, Article 119737.
https://doi.org/10.1016/j.biomaterials.2019.119737
Sibum,
I., Hagedoorn, P., Kluitman, M. P. G., Kloezen,
M., Frijlink, H. W., & Grasmeijer, F.
(2020). Dispersibility and Storage Stability Optimization of
High Dose Isoniazid Dry Powder Inhalation Formulations with
L-Leucine or Trileucine.
Pharmaceutics, 12(1), Article 24. https://doi.org/10.3390/pharmaceutics12010024
Yska,
J. P., Wanders, J. T. M., Odigie, B., Apers, J. A., Emous,
M., Totté, E. R. E., Boerma, E. C., Ubels,
F. L., Woerdenbag, H. J., Frijlink, H.
W., Wilffert, B., & Van Roon, E.
N. (2020). Effect of Roux-en-Y gastric bypass on the
bioavailability of metoprolol from immediate and controlled release
tablets: A single oral dose study before and after surgery.
European Journal of Hospital Pharmacy: Science and
Practice, 27(E1), e19–e24. https://doi.org/10.1136/ejhpharm-2018-001804
Boudewijn,
I. M., Lan, A., Faiz, A., Cox, C.
A., Brouwer, S., Schokker, S., Vroegop, S.
J., Nawijn, M. C., Woodruff, P. G., Christenson, S.
A., Hagedoorn, P., Frijlink, H. W., Choy,
D. F., Brouwer, U., Wisman, M.,
Postma, D. S., Fingleton, J., Beasley, R., van den
Berge, M., & Guryev, V. (2020). Nasal
gene expression changes with inhaled corticosteroid treatment in
asthma. Allergy, 75(1),
191-194. https://doi.org/10.1111/all.13952
Yska,
J. P., Punter, R. J., Woerdenbag, H. J., Emous,
M., Frijlink, H. W., Wilffert,
B., & Van Roon, E. N. (2019). A
gastrointestinal simulation system for dissolution of oral solid
dosage forms before and after Roux-en-Y gastric bypass.
European Journal of Hospital Pharmacy: Science and
Practice, 26(3), 152-156. https://doi.org/10.1136/ejhpharm-2017-001360
Cox,
C. A., Boudewijn, I. M., Vroegop, S. J.,
Schokker, S., Lexmond, A. J., Frijlink, H.
W., Hagedoorn, P., Vonk, J.
M., Farenhorst, M. P., ten Hacken, N. H.
T., Kerstjens, H. A. M., & van den
Berge, M. (2019). Associations of AMP and adenosine
induced dyspnea sensation to large and small airways dysfunction in
asthma. BMC Pulmonary Medicine,
19(1), Article 23. https://doi.org/10.1186/s12890-019-0783-0
Larmené-Beld,
K. H. M., Frijlink, H. W., & Taxis,
K. (2019). A systematic review and meta-analysis of
microbial contamination of parenteral medication prepared in a
clinical versus pharmacy environment. European
Journal of Clinical Pharmacology, 75(5),
609-617. https://doi.org/10.1007/s00228-019-02631-2
Sibum,
I., Hagedoorn, P., Frijlink, H.
W., & Grasmeijer, F. (2019).
Characterization and Formulation of Isoniazid for High-Dose
Dry Powder Inhalation. Pharmaceutics,
11(5), Article 233. https://doi.org/10.3390/pharmaceutics11050233
Janssen,
R., Wouters, E. F. M., Janssens, W., Daamen, W. F.,
Hagedoorn, P., de Wit, H. A. J. M., Serre, J.,
Gayan-Ramirez, G., Franssen, F. M. E., Reynaert, N. L., von der
Thusen, J. H., & Frijlink, H. W. (2019).
Copper-Heparin Inhalation Therapy To Repair Emphysema: A
Scientific Rationale. International Journal of
Chronic Obstructive Pulmonary Disease, 14,
2587-2602. https://doi.org/10.2147/COPD.S228411
Beugeling,
M., Amssoms, K., Cox, F., De Clerck, B., Van Gulck, E.,
Verwoerd, J., Kraus, G., Roymans, D., Baert, L., Frijlink, H.
W., & Hinrichs, W. (2019).
Development of a Stable Respiratory Syncytial Virus
Pre-Fusion Protein Powder Suitable for a Core-Shell Implant with a
Delayed Release in Mice: A Proof of Concept Study.
Pharmaceutics, 11(10), Article 510.
https://doi.org/10.3390/pharmaceutics11100510
Sibum,
I., Grasmeijer, F., Hagedoorn, P.,
& Frijlink, H. W. (2019). Formulating Amikacin for
dry powder inhalation. Journal of aerosol medicine
and pulmonary drug delivery, 32(2), A7-A7. https://doi.org/10.1089/jamp.2019.ab01.abstracts
Luinstra,
M., Isufi, V., de Jong, L., Rutgers, A. W. F.,
Hagedoorn, P., Puttenstein, J., van Laar,
T., & Frijlink, H. W. (2019).
Learning from Parkinson's patients: Usability of the Cyclops
dry powder inhaler. International Journal of
Pharmaceutics, 567, 118493. Article 118493. https://doi.org/10.1016/j.ijpharm.2019.118493
Tian,
Y., Orlu, M., Woerdenbag, H. J., Scarpa, M.,
Kiefer, O., Kottke, D., Sjoholm, E., Oblom, H., Sandler, N.,
Hinrichs, W. L. J., Frijlink, H. W.,
Breitkreutz, J., & Visser, J. C. (2019).
Oromucosal films: from patient centricity to production by
printing techniques. Expert Opinion on Drug
Delivery, 16(9), 981-993. https://doi.org/10.1080/17425247.2019.1652595
Beugeling,
M., Born, P., Amssoms, K., De Clerck, B., Van
Gulck, E., Frijlink, H. W., Grasmeijer, N., Kraus, G.,
Baert, L., & Hinrichs, W. (2019).
Ovalbumin-Containing Core-Shell Implants Suitable to
Obtain a Delayed IgG1 Antibody Response in Mice. Poster
session presented at AAPS PharmSci 360, San Antonio, United
States.
Luinstra,
M., Rutgers, W., van Laar, T.,
Grasmeijer, F., Begeman, A., Isufi, V., Steenhuis, L.,
Hagedoorn, P., de Boer, A., &
Frijlink, H. W. (2019). Pharmacokinetics and
tolerability of inhaled levodopa from a new dry-powder inhaler in
patients with Parkinson's disease. Therapeutic
advances in chronic disease, 10. https://doi.org/10.1177/2040622319857617
Tian,
Y., Visser, C., Woerdenbag,
H., Frijlink, H. W., & Hinrichs,
W. (2019). Printing biopharmaceuticals onto
orodispersible films. Poster session presented at AAPS
PharmSci 360, San Antonio, United States.
Tomar,
J., Tonnis, W. F., Patil, H. P., de Boer, A. H.,
Hagedoorn, P., Vanbever, R., Frijlink, H.
W., & Hinrichs, W. L. J. (2019).
Pulmonary immunization: deposition site is of minor relevance
for influenza vaccination but deep lung deposition is crucial for
hepatitis B vaccination. Acta Pharmaceutica Sinica
B, 9(6), 1231-1240. https://doi.org/10.1016/j.apsb.2019.05.003
Beugeling,
M., De Zee, J., Woerdenbag, H. J.,
Frijlink, H. W., Wilschut, J. C., &
Hinrichs, W. L. J. (2019). Respiratory syncytial virus
subunit vaccines based on the viral envelope glycoproteins intended
for pregnant women and the elderly. Expert review
of vaccines, 18(9), 935-950. https://doi.org/10.1080/14760584.2019.1657013
van
Dijk, F., Teekamp, N., Post, E., Schuppan, D.,
Kim, Y. O., Zuidema, J., Steendam, R., Klose, M. H. M.,
Meier-Menches, S. M., Casini, A., Horvatovich, P. L.,
Sijbrandi, N. J., Frijlink, H. W., Hinrichs, W.
L. J., Poelstra, K., Beljaars,
L., & Olinga, P. (2019). The
antifibrotic potential of a sustained release formulation of a PDGF
beta-receptor targeted rho kinase inhibitor.
Journal of Controlled Release, 296,
250-257. https://doi.org/10.1016/j.jconrel.2018.12.039
Bloemers,
J., Gerritsen, J., van Rooij, K., de Leede, L., van der Geest,
R., Frijlink, H. W., Koppeschaar, H. P. F., Olivier,
B., & Tuiten, A. (2019). The Effect of Food on the
Pharmacokinetics of Sildenafil after Single Administration of a
Sublingual Testosterone and Oral Sildenafil Combination Tablet in
Healthy Female Subjects. Journal of Sexual
Medicine, 16(9), 1433-1443. https://doi.org/10.1016/j.jsxm.2019.06.015
Ruigrok,
M., Tomar, J., Frijlink, H. W., Melgert,
B., Hinrichs, W., & Olinga, P.
(2019). The effects of oxygen concentration on cell death,
anti-oxidant transcription, acute inflammation, and cell
proliferation in precision-cut lung slices.
Scientific Reports, 9(1), Article
16239. https://doi.org/10.1038/s41598-019-52813-2
Beugeling,
M., Grasmeijer, N., Born, P., van der Meulen,
M., Kooij, van der, R., Schwengle, K., Baert, L.,
Amssoms, K., Frijlink, H. W., & Hinrichs,
W. (2019). The Mechanism Behind the Biphasic
Pulsatile Drug Release from Physically Mixed
Poly(DL-Lactic(-Co-Glycolic) Acid)-Based Compacts.
Poster session presented at AAPS PharmSci 360, San Antonio, United
States.
Gareb,
B., Posthumus, S., Beugeling, M., Koopmans,
P., Touw, D. J., Dijkstra, G.,
Kosterink, J. G. W., & Frijlink, H. W.
(2019). Towards the Oral Treatment of Ileo-Colonic
Inflammatory Bowel Disease with Infliximab Tablets: Development and
Validation of the Production Process.
Pharmaceutics, 11(9), Article 428.
https://doi.org/10.3390/pharmaceutics11090428
Murti,
Y. B., Hartini, Y. S., Hinrichs, W. L. J.,
Frijlink, H. W., & Setyaningsih, D. (2019). UV-Vis
spectroscopy to enable determination of the dissolution behavior of
solid dispersions containing curcumin and piperine.
Journal of Young Pharmacists, 11(1),
26-30. https://doi.org/10.5530/jyp.2019.11.6
Frijlink,
H. W. (2019). Wisselen van
medicijnen.
Sahal,
G., Woerdenbag, H. J., Hinrichs, W. L.
J., Visser, A., Tepper, P.
G., Quax, W. J., van der Mei, H.
C., & Bilkay, I. S. (2020). Antifungal and biofilm
inhibitory effect of Cymbopogon citratus (lemongrass) essential oil
on biofilm forming by Candida tropicalis isolates; an in vitro
study. Journal of ethnopharmacology,
246, Article 112188. https://doi.org/10.1016/j.jep.2019.112188
Tapia-Calle,
G., Born, P. A., Koutsoumpli, G.,
Gonzalez-Rodriguez, M. I., Hinrichs, W. L. J.,
& Huckriede, A. L. W. (2019). A PBMC-Based System
to Assess Human T Cell Responses to Influenza Vaccine Candidates In
Vitro. Vaccines, 7(4),
Article 181. https://doi.org/10.3390/vaccines7040181
Bigaeva,
E., Stribos, E. G. D., Mutsaers, H. A.
M., Piersma, B., Leliveld, A.
M., de Jong, I. J., Bank, R.
A., Seelen, M. A., van Goor, H.,
Wollin, L., Olinga, P., & Boersema,
M. (2020). Inhibition of tyrosine kinase receptor
signaling attenuates fibrogenesis in an ex vivo model of human
renal fibrosis. American journal of
physiology-Renal physiology, 318(1),
F117-F134. https://doi.org/10.1152/ajprenal.00108.2019
Jensen,
M. S., Mutsaers, H. A. M., Tingskov, S. J.,
Christensen, M., Madsen, M. G., Olinga, P., Kwon,
T.-H., & Norregaard, R. (2019). Activation of the
prostaglandin E-2 EP2 receptor attenuates renal fibrosis in
unilateral ureteral obstructed mice and human kidney slices.
Acta physiologica, 227(1), Article
e13291. https://doi.org/10.1111/apha.13291
Jensen,
M. S., Mutsaers, H. A. M., Tingskov, S. J.,
Christensen, M., Madsen, M. G., Olinga, P., Kwon,
T.-H., & Norregaard, R. (2019). Administration of a
selective prostaglandin E-2 receptor agonist attenuates renal
fibrosis in vitro and in vivo. FASEB
Journal, 33.
Prins,
G. H., Luangmonkong, T., Oosterhuis, D.,
Mutsaers, H. A. M., Dekker, F. J., &
Olinga, P. (2019). A Pathophysiological Model of
Non-Alcoholic Fatty Liver Disease Using Precision-Cut Liver
Slices. Nutrients, 11(3),
Article 507. https://doi.org/10.3390/nu11030507
Mutsaers,
H. A. M., Jensen, M. S., Olinga, P., &
Norregaard, R. (2019). Cyclooxygenase-2 Regulates the Renal
Expression of Indoleamine 2,3-dioxygenase. FASEB
Journal, 33.
Karsten,
R. E. H., Oosterhuis, D., van Wijk, L.
A., & Olinga, P. (2019). Ex Vivo Model in
Cholestasis Research. In M. Vinken (Ed.), Experimental
Cholestasis Research (pp. 351-362). (Methods in Molecular
Biology; Vol. 1981). Humana Press. https://doi.org/10.1007/978-1-4939-9420-5_23
Bigaeva,
E., Bomers, J. J. M., Biel, C., Mutsaers,
H. A. M., de Graaf, I. A. M., Boersema,
M., & Olinga, P. (2019). Growth
factors of stem cell niche extend the life-span of precision-cut
intestinal slices in culture: A proof-of-concept study.
Toxicology in Vitro, 59, 312-321. https://doi.org/10.1016/j.tiv.2019.05.024
Prins,
G. H., Jansen, Y. J. M., Oosterhuis,
D., Olinga, P., & Gier, K.
(2019). INDUCTION OF STEATOSIS IN HUMAN LIVER EX VIVO.
Hepatology, 70, 1311A-1311A.
van
Praagh, J. B., de Goffau, M. C., Bakker, I. S.,
van Goor, H., Harmsen, H. J. M., Olinga,
P., & Havenga, K. (2019). Mucus
Microbiome of Anastomotic Tissue During Surgery Has Predictive
Value for Colorectal Anastomotic Leakage. Annals
of Surgery, 269(5), 911-916. https://doi.org/10.1097/SLA.0000000000002651
Guo,
H., Verhoek, I. C., Prins, G. G. H., van der
Vlag, R., van der Wouden, P. E., van Merkerk,
R., Quax, W. J., Olinga, P.,
Hirsch, A. K. H., & Dekker, F. J. (2019).
Novel 15-Lipoxygenase-1 Inhibitor Protects Macrophages from
Lipopolysaccharide-Induced Cytotoxicity. Journal
of Medicinal Chemistry, 62(9), 4624-4637. https://doi.org/10.1021/acs.jmedchem.9b00212
de
Jong, I. E. M., Matton, A. P. M., van Praagh, J. B.,
van Haaften, W. T., Wiersema-Buist, J.,
van Wijk, L. A., Oosterhuis, D., Iswandana, R.,
Suriguga, S., Overi, D., Lisman, T., Carpino,
G., Gouw, A. S. H., Olinga, P., Gaudio,
E., & Porte, R. J. (2019). Peribiliary
glands are key in regeneration of the biliary epithelium after
severe ischemic bile duct injury during liver
transplantation. Transplantation,
103(8), 3-3. https://doi.org/10.1097/01.tp.0000580472.17422.db
Gore,
E., Bigaeva, E., Oldenburger, A., Ook, K. Y.,
Rippmann, J. F., Schuppan, D., Boersema, M.,
& Olinga, P. (2019). PI3K inhibition reduces
murine and human liver fibrogenesis in precisioncut liver
slices. Biochemical Pharmacology,
169, Article 113633. https://doi.org/10.1016/j.bcp.2019.113633
Prins,
G. H., Jansen, Y. J. M., Oosterhuis,
D., Dekker, F. J., Olinga,
P., & Gier, K. (2019).
POLYUNSATURATED FATTY ACIDS AND 5-LIPOXYGENASE IN
NON-ALCOHOLIC FATTY LIVER DISEASE.
Hepatology, 70, 1311A-1311A.
Bartucci,
R., Åberg, C., Boersma, Y. L.,
Olinga, P., & Salvati, A. (2019).
Precision-cut liver slices as a promising ex vivo model for
nanosafety studies. Toxicology
Letters, 314(Supplement), S204-S205.
Bigaeva,
E., Gore, E., Simon, E., Zwick, M., Oldenburger, A.,
de Jong, K. P., Hofker, H. S., Schlepütz,
M., Nicklin, P., Boersema, M., Rippmann, J. F.,
& Olinga, P. (2019). Transcriptomic
characterization of culture-associated changes in murine and human
precision-cut tissue slices. Archives of
toxicology, 93(12), 3549-3583. https://doi.org/10.1007/s00204-019-02611-6
Bartucci,
R., Salvati, A., Olinga, P., &
Boersma, Y. L. (2019). Vanin 1: Its Physiological Function
and Role in Diseases. International Journal of
Molecular Sciences, 20(16), Article 3891. https://doi.org/10.3390/ijms20163891
Herawati,
F., Yulia, R., Hak, E., Hartono, A. H., Michiels,
T., Woerdenbag, H. J., & Avanti, C. (2019).
A Retrospective Surveillance of the Antibiotics Prophylactic
Use of Surgical Procedures in Private Hospitals in
Indonesia. Hospital Pharmacy Europe,
54(5), 323-329. https://doi.org/10.1177/0018578718792804
2018
Gareb,
B., Dijkstra, G., Kosterink, J. G.
W., & Frijlink, H. W. (2019).
Development of novel zero-order release budesonide tablets
for the treatment of ileo-colonic inflammatory bowel disease and
comparison with formulations currently used in clinical
practice. International Journal of
Pharmaceutics, 554, 366-375. https://doi.org/10.1016/j.ijpharm.2018.11.019
Grasmeijer,
N., Tiraboschi, V., Woerdenbag, H. J., Frijlink,
H. W., & Hinrichs, W. L. J. (2019).
Identifying critical process steps to protein stability
during spray drying using a vibrating mesh or a two-fluid
nozzle. European Journal of Pharmaceutical
Sciences, 128, 152-157. https://doi.org/10.1016/j.ejps.2018.11.027
Tomar,
J., Patil, H. P., Bracho, G., Tonnis, W. F., Frijlink, H.
W., Petrovsky, N., Vanbever, R., Huckriede,
A., & Hinrichs, W. L. J. (2018).
Advax augments B and T cell responses upon influenza
vaccination via the respiratory tract and enables complete
protection of mice against lethal influenza virus challenge.
Journal of Controlled Release, 288,
199-211. https://doi.org/10.1016/j.jconrel.2018.09.006
Weerts,
Z. Z. R. M., Keszthelyi, D., Vork, L., Aendekerk, N. C. P.,
Frijlink, H. W., Brouwers, J. R. B. J., Neef, C., Jonkers,
D. M. A. E., & Masclee, A. A. M. (2018). A Novel
Ileocolonic Release Peppermint Oil Capsule for Treatment of
Irritable Bowel Syndrome: A Phase I Study in Healthy
Volunteers. Advances in therapy,
35(11), 1965-1978. https://doi.org/10.1007/s12325-018-0802-1
Sibum,
I., Hagedoorn, P., de Boer, A.
H., Frijlink, H. W., & Grasmeijer,
F. (2018). Challenges for pulmonary delivery of high
powder doses. International Journal of
Pharmaceutics, 548(1), 325-336. https://doi.org/10.1016/j.ijpharm.2018.07.008
Akkerman,
O. W., Grasmeijer, F., de Lange, W. C.
M., Kerstjens, H. A. M., de Vries, G.,
Bolhuis, M. S., Alffenaar, J.-W.,
Frijlink, H. W., Smith, G., Gajraj, R., de Zwaan, R.,
Hagedoorn, P., Dedicoat, M., van Soolingen, D., &
van der Werf, T. S. (2018). Cross border, highly
individualised treatment of a patient with challenging extensively
drug-resistant tuberculosis. European Respiratory
Journal, 51(3), Article 1702490. https://doi.org/10.1183/13993003.02490-2017
Kanojia,
G., Raeven, R. H. M., van der Maas, L., Bindels, T. H. E., van
Riet, E., Metz, B., Soema, P. C., Ten Have, R., Frijlink, H.
W., Amorij, J.-P., & Kersten, G. F. A. (2018).
Development of a thermostable spray dried outer membrane
vesicle pertussis vaccine for pulmonary immunization.
Journal of controlled release : official journal of the
Controlled Release Society, 286, 167-178. https://doi.org/10.1016/j.jconrel.2018.07.035
Tuiten,
A., van Rooij, K., Bloemers, J., Eisenegger, C., van Honk, J.,
Kessels, R., Kingsberg, S., Derogatis, L. R., de Leede, L.,
Gerritsen, J., Koppeschaar, H. P. F., Olivier, B., Everaerd,
W., Frijlink, H. W., Höhle, D., de Lange, R. P.
J., Böcker, K. B. E., & Pfaus, J. G. (2018).
Efficacy and safety of on-demand use of 2 treatments designed
for different etiologies of female sexual interest/arousal
disorder: 3 Randomized Clinical Trials. Journal of
Sexual Medicine, 15(2), 201-216. https://doi.org/10.1016/j.jsxm.2017.11.226
Kauppinen,
A., Broekhuis, J., Grasmeijer, N., Tonnis, W., Ketolainen,
J., Frijlink, H. W., & Hinrichs, W. L.
J. (2018). Efficient production of solid dispersions
by spray drying solutions of high solid content using a 3-fluid
nozzle. European Journal of Pharmaceutics and
Biopharmaceutics, 123, 50-58. https://doi.org/10.1016/j.ejpb.2017.11.009
Sibum,
I., Grasmeijer, F., Hagedoorn, P.,
& Frijlink, H. W. (2018). FORMULATING ISONIAZID
FOR DRY POWDER INHALATION BY SPRAY DRYING. Journal
of aerosol medicine and pulmonary drug delivery,
31(2), A2-A2.
Broesder,
A., Teekamp, N., van Dijk, F., Beljaars,
E., Hinrichs, W., Poelstra,
K., Frijlink, H. W., & Olinga,
P. (2018). Formulation of biodegradable
microspheres for the sustained release of PDGFβ-receptor
directed HSA targeted to fibrotic tissue. Poster
session presented at 11th World Meeting on Pharmaceutics,
Biopharmaceutics and Pharmaceutical Technology, Granada,
Spain.
Tuiten,
A., Michiels, F., Böcker, K. B., Höhle, D., van Honk, J.,
de Lange, R. P., van Rooij, K., Kessels, R., Bloemers, J.,
Gerritsen, J., Janssen, P., de Leede, L., Meyer, J.-J., Everaerd,
W., Frijlink, H. W., Koppeschaar, H. P., Olivier, B.,
& Pfaus, J. G. (2018). Genotype scores predict drug
efficacy in subtypes of female sexual interest/arousal disorder: A
double-blind, randomized, placebo-controlled cross-over
trial. Women's health (London,
England), 14. https://doi.org/10.1177/1745506518788970
Frijlink,
H. W. (2018). Moeiteloos inhaleren.
New scientist, (Special 'Engineering in
Groningen'), 28-29.
Tian,
Y., Visser, J. C., Klever, J. S.,
Woerdenbag, H. J., Frijlink, H. W., &
Hinrichs, W. L. J. (2018). Orodispersible films based
on blends of trehalose and pullulan for protein delivery.
European Journal of Pharmaceutics and
Biopharmaceutics, 133, 104-111. https://doi.org/10.1016/j.ejpb.2018.09.016
Amssoms,
K., Born, P. A., Beugeling, M., De
Clerck, B., Van Gulck, E., Hinrichs, W. L. J.,
Frijlink, H. W., Grasmeijer, N., Kraus, G., Sutmuller, R.,
Simmen, K., & Baert, L. (2018). Ovalbumin-containing
core-shell implants suitable to obtain a delayed IgG1 antibody
response in support of a biphasic pulsatile release profile in
mice. PLoS ONE, 13(8),
e0202961. Article 0202961. https://doi.org/10.1371/journal.pone.0202961
Visser,
J. C., Ten Seldam, I. E. J., van der Linden, I. J.,
Hinrichs, W. L. J., Veenendaal, R. F. H., Dijkers, E. C.
F., & Woerdenbag, H. J. (2018). Comparison
of Rheological and Sedimentation Behavior of Commercially Available
Suspending Vehicles for Oral Pharmaceutical Preparations.
International journal of pharmaceutical
compounding, 22(3), 247-251. https://www.ijpc.com/Abstracts/Abstract.cfm?ABS=4480
Tomar,
J., Biel, C., de Haan, C. A. M., Rottier, P. J. M.,
Petrovsky, N., Frijlink, H. W., Huckriede,
A., Hinrichs, W. L. J., & Peeters, B.
(2018). Passive inhalation of dry powder influenza vaccine
formulations completely protects chickens against H5N1 lethal viral
challenge. European Journal of Pharmaceutics and
Biopharmaceutics, 133, 85-95. https://doi.org/10.1016/j.ejpb.2018.10.008
Bhide,
Y., Tomar, J., Dong, W., de Vries-Idema,
J., Frijlink, H. W., Huckriede,
A., & Hinrichs, W. L. J. (2018).
Pulmonary delivery of influenza vaccine formulations in
cotton rats: Site of deposition plays a minor role in the
protective efficacy against clinical isolate o H1N1pdm
virus. Drug Delivery, 25(1),
533-545. https://doi.org/10.1080/10717544.2018.1435748
Ruigrok,
M. J. R., Xian, J.-L., Frijlink, H. W.,
Melgert, B. N., Hinrichs, W. L. J., &
Olinga, P. (2018). siRNA-mediated protein knockdown in
precision-cut lung slices. European Journal of
Pharmaceutics and Biopharmaceutics, 133,
339-348. https://doi.org/10.1016/j.ejpb.2018.11.005
Ruigrok,
M., Xian, J. L., Frijlink, H. W.,
Melgert, B., Hinrichs, W., & Olinga,
P. (2018). siRNA-mediated protein knockdown in
precision-cut lung slices. Poster session presented at
AAPS PharmSci360, Washington, District of Columbia, United
States.
Ruigrok,
M., Maggan, N., Frijlink, H. W., Melgert,
B., Olinga, P., & Hinrichs, W.
(2018). siRNA-mediated RNA interference in precision-cut
tissue slices prepared from mouse lung. Poster session
presented at 11th World Meeting on Pharmaceutics, Biopharmaceutics
and Pharmaceutical Technology, Granada, Spain.
Beugeling,
M., Grasmeijer, N., Born, P. A., van der
Meulen, M., van der Kooij, R. S., Schwengle, K.,
Baert, L., Amssoms, K., Frijlink, H. W., &
Hinrichs, W. L. J. (2018). The mechanism behind the
biphasic pulsatile drug release from physically mixed
poly(DL-lactic(-co-glycolic) acid)-based compacts.
International Journal of Pharmaceutics,
551(1-2), 195-202. https://doi.org/10.1016/j.ijpharm.2018.09.025
de
Jong, I. E. M., Matton, A. P. M., van Praagh, J. B.,
van Haaften, W. T., Wiersema-Buist, J., van
Wijk, L. A., Oosterhuis, D., Iswandana, R., Suriguga,
S., Overi, D., Lisman, T., Carpino, G., Gouw, A.
S. H., Olinga, P., Gaudio, E., &
Porte, R. J. (2019). Peribiliary glands are key in
regeneration of the human biliary epithelium after severe bile duct
injury. Hepatology, 69(4),
1719-1734. https://doi.org/10.1002/hep.30365
Prins,
G., Oosterhuis, D., Van Wijk, L. A., Shelton,
L., & Olinga, P. (2018). Developing an Ex
Vivo Non-Alcoholic Fatty Liver Disease Model Using Human
Livers. Hepatology, 68,
1008A-1009A.
Luangmonkong,
T., Suriguga, S., Adhyatmika, A., Adlia, A., Oosterhuis,
D., Suthisisang, C., de Jong, K. P.,
Mutsaers, H. A. M., & Olinga, P. (2018).
In vitro and ex vivo anti-fibrotic effects of LY2109761, a
small molecule inhibitor against TGF-β.
Toxicology and Applied Pharmacology,
355, 127-137. https://doi.org/10.1016/j.taap.2018.07.001
Sharma,
M., Patra, B., Hale, W., Karsten, R. E. H., Salentijn,
G. I. J., Grajewski, M., Fuhrer, E., Zakhurdaeva, A.,
Mager, D., Korvink, J., Olinga, P., Verpoorte,
E., & Utz, M. (2018). Micro magnetic resonance
imaging of murine liver tissue slices on a microfluidic perfusion
device. In 22nd International Conference on Miniaturized
Systems for Chemistry and Life Sciences, MicroTAS 2018 (pp.
1722-1724). (22nd International Conference on Miniaturized Systems
for Chemistry and Life Sciences, MicroTAS 2018; Vol. 3). Chemical
and Biological Microsystems Society .
Grajewski,
M., Salentijn, G. I. J., Karsten, R. E.
H., Olinga, P., & Verpoorte,
E. (2018). Real-time monitoring of biliary transport
in precision-cut liver slices. In 22nd International
Conference on Miniaturized Systems for Chemistry and Life Sciences,
MicroTAS 2018 (pp. 1644-1646). (22nd International Conference
on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS
2018; Vol. 3). Chemical and Biological Microsystems Society .
Touw,
D., Koc, S., Meints, J. W., Woerdenbag,
H., Stoffers, S., & Pauline, K. (2018). Giftig
gevolg van kauwen op blaadjes laurierkers.
Pharmaceutisch Weekblad, 153(36), 18
- 19. https://www.pw.nl/achtergrond/2018/giftig-gevolg-van-kauwen-op-blaadjes-laurierkers
Tian,
Y., Visser, J. C., Frijlink, H.
W., & Woerdenbag, H. (2018). Pullulan
and trehalose based films for protein delivery in the oral
cavity. Journal of Hepatology.
2017
Lexmond,
A. J., Boudewijn, I. M., Hagedoorn, P.,
Schokker, S., Cox, C. A., Vonk, J.
M., ten Hacken, N. H. T., Frijlink, H.
W., Vroegop, S. J., & van den Berge,
M. (2018). Bronchial Provocation Testing Can Be
Improved by Using Dry Powder Adenosine Instead of Nebulized
Adenosine Monophosphate. American Journal of
Respiratory and Critical Care Medicine,
197(3), 391-394. https://doi.org/10.1164/rccm.201704-0715LE
van
Dijk, F., Teekamp, N., Beljaars, L.,
Post, E., Zuidema, J., Steendam, R., Kim, Y. O.,
Frijlink, H. W., Schuppand, D., Poelstra,
K., Hinrichs, W. L. J., & Olinga,
P. (2018). Pharmacokinetics of a sustained release
formulation of PDGFβ-receptor directed carrier proteins to
target the fibrotic liver. Journal of Controlled
Release, 269, 258-265. https://doi.org/10.1016/j.jconrel.2017.11.029
Teekamp,
N., Tian, Y., Visser, J. C.,
Olinga, P., Frijlink, H. W., Woerdenbag,
H. J., & Hinrichs, W. L. J. (2017).
Addition of Pullulan to Trehalose Glasses Improves the
Stability of β-Galactosidase at High Moisture
Conditions. Carbohydrate Polymers,
176, 374-380. https://doi.org/10.1016/j.carbpol.2017.08.084
Patil,
H. P., Herrera Rodriguez, J., de Vries-Idema,
J., Meijerhof, T., Frijlink, H.
W., Hinrichs, W. L. J., & Huckriede,
A. (2017). Adjuvantation of Pulmonary-Administered
Influenza Vaccine with GPI-0100 Primarily Stimulates Antibody
Production and Memory B Cell Proliferation.
Vaccines, 5(3). https://doi.org/10.3390/vaccines5030019
Mensink,
M. A., Frijlink, H. W., van der Voort
Maarschalk, K., & Hinrichs, W. L. J.
(2017). How sugars protect proteins in the solid state and
during drying (review): Mechanisms of stabilization in relation to
stress conditions. European Journal of
Pharmaceutics and Biopharmaceutics, 114,
288-295. https://doi.org/10.1016/j.ejpb.2017.01.024
Mensink,
M., Hinrichs, W., Frijlink, H. W.,
& van der Voort Maarschalk, K. (2017). Kleine,
flexibele suikers meest geschikt voor stabilisatie eiwit.
Pharmaceutisch Weekblad, 43. http://www.pw.nl/achtergrond/2017/kleine-flexibele-suikers-meest-geschikt-voor-stabilisatie-eiwit
Teekamp,
N., Van Dijk, F., Broesder, A., Evers,
M., Zuidema, J., Steendam, R., Post, E.,
Hillebrands, J. L., Frijlink, H. W.,
Poelstra, K., Beljaars, L., Olinga,
P., & Hinrichs, W. L. J. (2017).
Polymeric microspheres for the sustained release of a
protein-based drug carrier targeting the PDGFβ-receptor in the
fibrotic kidney. International Journal of
Pharmaceutics, 534(1-2), 229-236. https://doi.org/10.1016/j.ijpharm.2017.09.072
Ruigrok,
M. J. R., Maggan, N., Willaert, D., Frijlink, H.
W., Melgert, B. N., Olinga,
P., & Hinrichs, W. L. J. (2017).
siRNA-mediated RNA interference in precision-cut tissue
slices prepared from mouse lung and kidney. The
AAPS Journal, 19(6), 1855-1863. https://doi.org/10.1208/s12248-017-0136-y
van
Dijk, F., Teekamp, N., Beljaars, L.,
Post, E., Kim, Y. O., Frijlink, E.,
Hinrichs, W., Schuppan, D., Poelstra, K.,
& Olinga, P. (2017). Therapeutic proteins in the
treatment of liver fibrosis: The antifibrotic potential of a
sustained release formulation for a PDGF beta-receptor targeted
rho-kinase inhibitor. Hepatology,
66, 217A.
Mensink,
M. A., S ̌ib í k, J., Frijlink, H. W.,
Maarschalk, K. V. D. V., Hinrichs, W. L. J.,
& Zeitler, J. A. (2017). Thermal Gradient Mid- and
Far-Infrared Spectroscopy as Tools for Characterization of Protein
Carbohydrate Lyophilizates. Molecular
pharmaceutics, 14(10), 3550-3557. https://doi.org/10.1021/acs.molpharmaceut.7b00568
Van
Dijk, F., Teekamp, N., Beljaars, L.,
Post, E., Schuppan, D., Kim, Y. O., Poelstra,
K., Frijlink, E., Hinrichs,
W., & Olinga, P. (2017). Towards
clinical use of targeted therapies for liver fibrosis: development
of a sustained release formulation for therapeutic proteins.
Journal of Hepatology, 66(1),
S44-S44.
Caviglia,
J. M., Yan, J., Jang, M.-K., Gwak, G.-Y., Affo, S., Yu, L.,
Olinga, P., Friedman, R. A., Chen, X., & Schwabe, R. F.
(2018). MicroRNA-21 and Dicer are Dispensable for Hepatic
Stellate Cell Activation and the Development of Liver
Fibrosis. Hepatology, 67(6).
https://doi.org/10.1002/hep.29627
Visser,
J. C., Weggemans, O. A. F., Boosman, R.
J., Loos, K. U., Frijlink, H. W.,
& Woerdenbag, H. J. (2017). Increased drug load
and polymer compatibility of bilayered orodispersible films.
European Journal of Pharmaceutical Sciences,
107, 183-190. https://doi.org/10.1016/j.ejps.2017.07.010
Alting,
E. K., Riphagen, L. M., Schuiling-Veninga, C. C. M.,
Brouwers, J. R. B. J., & Woerdenbag, H. J. (2017).
Is er een plaats voor voedingsmiddelen verrijkt met
fytosterolen bij cardiovasculair risicomanagement? Kritische
analyse van de bewijskracht voor cholesterol-verlaging.
Pharmaceutisch Weekblad, 152(15),
20-32. https://www.knmp.nl/resolveuid/90b1976595c54359a3239a7fbc2e0a3b
Alting,
E. K., Riphagen, LM., Schuiling-Veninga, C. C. M.,
Brouwers, J. R. B. J., & Woerdenbag, H. (2017).
Is er een plaats voor voedingsmiddelen verrijkt met
fytosterolen bij cardiovasculair risicomanagement? Kritische
analyse van de bewijskracht voor cholesterolverlaging.
Nederlands Platform voor Farmaceutisch
Onderzoek, 2, 1-13. Article A 1641.
Jacobs,
M. S., Luinstra, M., Moes, J. R., Chan, T. C.
Y., Minovic, I., Frijlink, H. W.,
& Woerdenbag, H. J. (2017). Ready-to-use
parenteral amiodarone: A feasibility study towards a long-term
stable product formulation. European Journal of
Hospital Pharmacy: Science and Practice,
24(2), 110-114. https://doi.org/10.1136/ejhpharm-2015-000860
Gerrits,
E., Woerdenbag, H., Luurtsema, G.,
de Hooge, M., & Boersma, H. (2017).
The added value of Good Manufacturing Practices (GMP) in the
production of radiopharmaceuticals. In The added value
of Good Manufacturing Practice (GMP) in the production of
radiopharmaceuticals (pp. 59-67). Springer. https://doi.org/10.1007/978-3-319-33531-5_3
Woerdenbag,
H. J., Bos, R., & Scheffer, J. J. C.
(2017). Valerian: Quality assurance of the crude drug and its
preparations. In P. Houghton (Ed.), Valerian: The Genus
Valeriana (pp. 101-128). Routledge. https://doi.org/10.1201/9780203734483
Jacobs,
M. S., Hemminga, W. L., Woerdenbag, H. J.,
Bouma, M., & Moes, J. R. (2017). Zero-residual syringe
als verpakkingsmateriaal voor bevacizumab als intravitreale
injectie - Antwoord van de auteurs. Pharmaceutisch
Weekblad, 152(3).
2016
Visser,
J., Eugresya, G., Hinrichs, W., Tjandrawinata,
R., Avanti, C., Frijlink, H. W., &
Woerdenbag, H. (2017). Development of orodispersible
films with selected Indonesian medicinal plant extracts.
Journal of Herbal Medicine, 7,
37-46. https://doi.org/10.1016/j.hermed.2016.10.002
Grasmeijer,
N., Frijlink, H. W., & Hinrichs, W. L.
J. (2016). An adaptable model for growth and/or
shrinkage of droplets in the respiratory tract during inhalation of
aqueous particles. Journal of Aerosol
Science, 93, 21-34. https://doi.org/10.1016/j.jaerosci.2015.11.011
Setyaningsih,
D., Murti, Y. B., Martono, S., Hinrichs, W. L. J.,
Hertiani, T., & Fudholi, A. (2016). A novel reversed
phase high performance liquid chromatography method to accurately
determine low concentrations of curcumin in rat plasma.
International Journal of Pharmaceutical and Clinical
Research, 8(5), Suppl. 377-386.
Teekamp,
N., van Dijk, F., Beljaars, E.,
Hinrichs, W., Steendam, R., Zuidema, J., Poelstra,
K., Frijlink, H. W., & Olinga,
P. (2016). Biodegradable microspheres for the
sustained release of PDGF-receptor directed pPB-HSA targeted to the
fibrotic kidney. Abstract from FIGON Dutch Medicine
Days, Ede, Netherlands.
Teekamp,
N., van Dijk, F., Beljaars, E.,
Hinrichs, W., Poelstra, K., Frijlink, H.
W., & Olinga, P. (2016).
Biodegradable microspheres for the sustained release of
PDGF-receptor directed PPB-HSA targeted to the fibrotic
kidney. Poster session presented at Congress on
Innovation in Drug Delivery, Antibes, France.
Teekamp,
N., van Dijk, F., Beljaars, E.,
Post, E., Hinrichs, W., Poelstra,
K., & Olinga, P. (2016).
Biodegradable microspheres for the sustained release of
ppB-HSA to target PDGFβ-receptors in fibrotic
tissues. Poster session presented at 14th European
Symposium on Controlled Drug Delivery (ESCDD), Egmond aan Zee,
Netherlands.
Frijlink,
H. W., Grasmeijer, N., Hinrichs, W. L. J.,
Amssoms, K. I. E., & Baert, L. E. C. (2016). Compacted Solid Dosage Form. (Patent No.
WO2016020308). https://worldwide.espacenet.com/publicationDetails/originalDocument?CC=WO&NR=2016020308A1&KC=A1&FT=D&ND=3&date=20160211&DB=&locale=en_EP
Maurer,
J. M., Hofman, S., Schellekens, R. C. A., Tonnis, W. F.,
Dubois, A. O. T., Woerdenbag, H. J., Hinrichs,
W. L. J., Kosterink, J. G. W., &
Frijlink, H. W. (2016). Development and potential
application of an oral ColoPulse infliximab tablet with colon
specific release: A feasibility study.
International Journal of Pharmaceutics,
505(1-2), 175-186. https://doi.org/10.1016/j.ijpharm.2016.03.027
Tomar,
J., Born, P. A., Frijlink, H. W.,
& Hinrichs, W. L. J. (2016). Dry influenza
vaccines: towards a stable, effective and convenient alternative to
conventional parenteral influenza vaccination.
Expert review of vaccines, 15(11),
1431-1447. https://doi.org/10.1080/14760584.2016.1182869
Mensink,
M. A., Nethercott, M. J., Hinrichs, W. L. J.,
Maarschalk, K. V. D. V., Frijlink, H. W.,
Munson, E. J., & Pikal, M. J. (2016). Influence of
Miscibility of Protein-Sugar Lyophilizates on Their Storage
Stability. Aaps journal,
18(5), 1225-1232. https://doi.org/10.1208/s12248-016-9937-7
Grasmeijer,
N., Frijlink, H. W., & Hinrichs, W. L.
J. (2016). Model to predict inhomogeneous
protein-sugar distribution in powders prepared by spray
drying. Journal of Aerosol Science,
101, 22-33. https://doi.org/10.1016/j.jaerosci.2016.07.012
Ruigrok,
M., Frijlink, H. W., & Hinrichs,
W. (2016). Pulmonary administration of small
interfering RNA: The route to go? Journal of
Controlled Release, 235, 14-23. https://doi.org/10.1016/j.jconrel.2016.05.054
Visser,
J. C., Woerdenbag, H. J., Hanff, L. M.,
& Frijlink, H. W. (2017). Personalized Medicine in
Pediatrics: The Clinical Potential of Orodispersible Films.
Aaps pharmscitech, 104(5),
1292-1300. https://doi.org/10.1208/s12249-016-0515-1
Cremers,
T., Flik, G., Frijlink, H.
W., & Woerdenbag, H. J. (2016). Body Sculpting. (Patent No.
WO2016060564). https://worldwide.espacenet.com/publicationDetails/originalDocument?CC=WO&NR=2016060564A1&KC=A1&FT=D&ND=3&date=20160421&DB=&locale=en_EP
Jacobs,
M. S., Hemminga, W., Woerdenbag, H., Bouma, M., &
Moes, J. R. (2016). Kwalificatie van de zero-residual syringe
(Zeringe) als verpakkingsmateriaal voor bevacizumab als
intravitreale injectie. Pharmaceutisch Weekblad
Wetenschappelijk Platform, 1-6.
Krampe,
R., Visser, C., Frijlink, H. W.,
Breitkreutz, J., Woerdenbag, H. J., & Preis, M.
(2016). Oromucosal film preparations: Points to consider for
patient centricity and manufacturing processes.
Expert Opinion on Drug Delivery,
13(4), 493-506. https://doi.org/10.1517/17425247.2016.1118048
2015
Patil,
H. P., Murugappan, S., de Vries-Idema, J.,
Meijerhof, T., de Haan, A., Frijlink, H.
W., Wilschut, J., Hinrichs, W. L.
J., & Huckriede, A. (2015).
Comparison of adjuvants for a spray freeze-dried whole
inactivated virus influenza vaccine for pulmonary
administration. European Journal of Pharmaceutics
and Biopharmaceutics, 93, 231-241. https://doi.org/10.1016/j.ejpb.2015.04.004
Murugappan,
S., Frijlink, H. W., Petrovsky, N., &
Hinrichs, W. L. J. (2015). Enhanced pulmonary
immunization with aerosolized inactivated influenza vaccine
containing delta inulin adjuvant. European Journal
of Pharmaceutical Sciences, 66, 118-122. https://doi.org/10.1016/j.ejps.2014.10.008
Mensink,
M. A., Van Bockstal, P.-J., Pieters, S., De Meyer, L.,
Frijlink, H. W., van der Voort Maarschalk,
K., Hinrichs, W. L. J., & De Beer, T.
(2015). In-line near infrared spectroscopy during
freeze-drying as a tool to measure efficiency of hydrogen bond
formation between protein and sugar, predictive of protein storage
stability. International Journal of
Pharmaceutics, 792-800. https://doi.org/10.1016/j.ijpharm.2015.11.030
Mensink,
M. A., Frijlink, H. W., Maarschalk, K. V. D.
V., & Hinrichs, W. L. J. (2015).
Inulin, a flexible oligosaccharide I: Review of its
physicochemical characteristics. Carbohydrate
Polymers, 130, 405-419. https://doi.org/10.1016/j.carbpol.2015.05.026
Mensink,
M. A., Frijlink, H. W., van der Voort
Maarschalk, K., & Hinrichs, W. L. J.
(2015). Inulin, a flexible oligosaccharide. II: Review of its
pharmaceutical applications. Carbohydrate
Polymers, 134, 418-428. https://doi.org/10.1016/j.carbpol.2015.08.022
Visser,
C., Woerdenbag, H. J., Crediet, S., Gerrits,
E., Lesschen, M. A., Hinrichs, W. L. J., Breitkreutz,
J., & Frijlink, H. W. (2015). Orodispersible
films in individualized pharmacotherapy: The development of a
formulation for pharmacy preparations.
International Journal of Pharmaceutics,
478(1), 155-163. https://doi.org/10.1016/j.ijpharm.2014.11.013
Hinrichs,
W., & Dreijer - van der Glas, S. (2015). Physical
Chemistry. In Practical Pharmaceutics, an international
guideline for the preparation care and use of medicinal
products (pp. 357-382). Springer. https://doi.org/10.1007/978-3-319-15814-3_18
Stanković,
M., Frijlink, H. W., & Hinrichs, W. L.
J. (2015). Polymeric formulations for drug release
prepared by hot melt extrusion: application and
characterization. Drug Discovery
Today, 20(7), 812-823. https://doi.org/10.1016/j.drudis.2015.01.012
Teekamp,
N., Duque , L. F., Frijlink, H. W., Hinrichs, W.
L., & Olinga, P. (2015). Production
methods and stabilization strategies for polymer-based
nanoparticles and microparticles for parenteral delivery of
peptides and proteins. Expert Opinion on Drug
Delivery, 12(8), 1311-1331. https://doi.org/10.1517/17425247.2015.1003807
Stanković,
M., Hiemstra, C., de Waard, H., Zuidema, J., Steendam, R.,
Frijlink, H. W., & Hinrichs, W. L. J.
(2015). Protein release from water-swellable
poly(d,l-lactide-PEG)-b-poly(ϵ-caprolactone) implants.
International Journal of Pharmaceutics,
480(1-2), 73-83. https://doi.org/10.1016/j.ijpharm.2015.01.007
Teekamp,
N., Olinga, P., Hinrichs, W., &
Frijlink, H. W. (2015). Protein Stability during
Hot Melt Extrusion: The Effect of Extrusion Temperature,
Hydrophilicity of Polymers and Sugar Glass
Pre-stabilization. Poster session presented at
Biopharmacy Day 2015, Leuven, Belgium.
Teekamp,
N., Olinga, P., Frijlink, H. W.,
& Hinrichs, W. (2015). Protein Stability
during Hot Melt Extrusion: The Effect of Extrusion Temperature,
Hydrophilicity of Polymers and Sugar Glass
Pre-stabilization. Poster session presented at AAPS
Annual Meeting and Exposition, Orlando, United States. http://abstracts.aaps.org/Verify/AAPS2015/PosterSubmissions/R6255.pdf
Tonnis,
W. F., Huckriede, A. L. W., Hinrichs, W. L.
J., & Frijlink, H. W. (2015).
Pulmonary administration of subunit vaccines. In C.
Foged, T. Rades, Y. Perrie, & S. Hook (Eds.), Subunit
Vaccine Delivery (pp. 307-329). (Advances in Delivery Science
and Technology). Springer. https://doi.org/10.1007/978-1-4939-1417-3_16
Visser,
J. C., Dohmen, W. M. C., Hinrichs, W. L. J.,
Breitkreutz, J., Frijlink, H. W., &
Woerdenbag, H. J. (2015). Quality by design approach
for optimizing the formulation and physical properties of
extemporaneously prepared orodispersible films.
International Journal of Pharmaceutics,
485(1-2), 70-76. https://doi.org/10.1016/j.ijpharm.2015.03.005
Tonnis,
W. F., Mensink, M. A., de Jager, A., Maarschalk, K. V. D.
V., Frijlink, H. W., & Hinrichs, W.
L. J. (2015). Size and molecular flexibility of sugars
determine the storage stability of freeze-dried proteins.
Molecular pharmaceutics, 12(3),
684-694. https://doi.org/10.1021/mp500423z
Beugeling,
M., Ekoume, F., Woerdenbag, H. J.,
Luurtsema, G., Lub-de Hooge, M. N., Touw,
D. J., Rubow, S. M., & Boersma, H. H.
(2015). Assessment of microbiological monitoring for the
evaluation of GMP-compliance at a department of Nuclear Medicine
and Molecular Imaging of the University Medical Center
Groningen. European Journal of Nuclear Medicine
and Molecular Imaging, 42(1), 486.
Woerdenbag,
H., Sznitowska, M., & Bouwman-Boer, Y. (2015).
Basic Operations. In Practical Pharmaceutics, An
international guideline for the preparation care and use of
medicinal products (pp. 651-676). Springer. https://doi.org/10.1007/978-3-319-15814-3_29
Frijlink,
H. W., Touw, D., & Woerdenbag,
H. (2015). Biopharmaceutics. In Practical
Pharmaceutics, An international guideline for the preparation care
and use of medicinal products (pp. 323-346). Springer. https://doi.org/10.1007/978-3-319-15814-3_16
Maurer,
J. M., Schellekens, R. C. A., van Rieke, H. M., Wanke, C.,
Iordanov, V., Stellaard, F., Wutzke, K. D., Dijkstra,
G., van der Zee, M., Woerdenbag, H. J.,
Frijlink, H. W., & Kosterink, J. G. W.
(2015). Gastrointestinal pH and Transit Time Profiling in
Healthy Volunteers Using the IntelliCap System Confirms
Ileo-Colonic Release of ColoPulse Tablets. PLoS
ONE, 10(7), Article e0129076. https://doi.org/10.1371/journal.pone.0129076
Haas,
S., Woerdenbag, H., & Sznitowska, M. (2015).
Rectal and Vaginal. In Practical Pharmaceutics, An
international guideline for the preparation care and use of
medicinal products (pp. 189-227). Article 11 Springer. https://doi.org/10.1007/978-3-319-15814-3_11
de
Roo, F. M., Hilgerink, K., Kosterink, J. G. W.,
Luurtsema, G., Woerdenbag, H. J., &
Boersma, H. H. (2015). Tracer application in
cardiovascular imaging: A triple jump. In R. Slart, R. Tio,
P. Elsinga, & M. Schwaiger (Eds.), Autonomic Innervation of
the Heart: Role of Molecular Imaging (pp. 137-159). Springer.
https://doi.org/10.1007/978-3-662-45074-1_7
2014
Tonnis,
W. F., Bagerman, M., Weij, M., Sjollema,
J., Frijlink, H. W., Hinrichs, W. L.
J., & de Boer, A. H. (2014). A novel
aerosol generator for homogenous distribution of powder over the
lungs after pulmonary administration to small laboratory
animals. European Journal of Pharmaceutics and
Biopharmaceutics, 88(3), 1056-1063. https://doi.org/10.1016/j.ejpb.2014.10.011
Yska,
J. P., Punter, R. J., Woerdenbag, H. J., Apers, J. A.,
Emous, M., Totte, E., Frijlink, H. W., Wilffert,
B., & van Roon, E. N. (2014). A
GASTROINTESTINAL SIMULATION SYSTEM (GISS) FOR DISSOLUTION OF DRUGS
BEFORE AND AFTER ROUX-EN-Y GASTRIC BYPASS: FIRST RESULTS.
British Journal of Clinical Pharmacology,
78(4), 774-774. https://doi.org/10.1111/bcp.12400
Elfahmi,
Woerdenbag, H. J., & Kayser, O. (2014). Jamu:
Indonesian traditional herbal medicine towards rational
phytopharmacological use. Journal of Herbal
Medicine, 4(2), 51-73. https://doi.org/10.1016/j.hermed.2014.01.002
Gechev,
T. S., Hille, J., Woerdenbag, H. J.,
Benina, M., Mehterov, N., Toneva, V., Fernie, A. R., &
Mueller-Roeber, B. (2014). Natural products from resurrection
plants: Potential for medical applications.
Biotechnology Advances, 32(6),
1091-1101. https://doi.org/10.1016/j.biotechadv.2014.03.005
2013
Maurer,
J. M., Schellekens, R. C. A., Van Rieke, H. M., Stellaard,
F., Wutzke, K. D., Buurman, D. J., Dijkstra, G.,
Woerdenbag, H. J., Frijlink, H. W., &
Kosterink, J. G. W. (2013). ColoPulse tablets perform
comparably in healthy volunteers and Crohn's patients and show no
influence of food and time of food intake on
bioavailability. Journal of controlled release :
official journal of the Controlled Release Society,
172(3), 618-624. https://doi.org/10.1016/j.jconrel.2013.09.021
Schellekens,
R. C. A., Stellaard, F., Woerdenbag, H. J.,
Frijlink, H. W., & Kosterink, J. G. W.
(2013). Erratum: Applications of stable isotopes in clinical
pharmacology (vol 72, pg 879, 2011). British
Journal of Clinical Pharmacology, 75(4), 1171.
https://doi.org/10.1111/bcp.12107
Woerdenbag,
H., Visser, C., & Frijlink, H.
(2013). Pharmacy preparations, customized quality in
Dutch clinical care. 19-22. Pharma Indochina VIII.
ASEAN Pharmacy - Integration for development, Hanoi, Viet
Nam.
Woerdenbag,
H., & Brouwers, J. R. B. J. (2013). Traditionele
geneeskunde in Vietnam. Nederlands Tijdschrift
voor Fytotherapie, 1, 9-13.
2012
Maurer,
M. J. M., Schellekens, R. C. A., Wutzke, K. D.,
Dijkstra, G., Woerdenbag, H. J.,
Frijlink, H. W., Kosterink, J. G. W., &
Stellaard, F. (2012). A non-invasive, low-cost study design
to determine the release profile of colon drug delivery systems: A
feasibility study. Pharmaceutical
Research, 29(8), 2070-2078. https://doi.org/10.1007/s11095-012-0735-3
Tu,
H. A., Vu, H. D., Rozenbaum, M. H., Woerdenbag, H.
J., & Postma, M. J. (2012). A review
of the literature on the economics of vaccination against
TB. Expert review of vaccines,
11(3), 303-317. https://doi.org/10.1586/ERV.11.197
Tu,
H. A. T., de Vries, R., Woerdenbag, H. J., Li, S. C.,
Le, H. H., van Hulst, M., & Postma, M.
J. (2012). Cost-Effectiveness Analysis of Hepatitis B
Immunization in Vietnam: Application of Cost-Effectiveness
Affordability Curves in Health Care Decision Making.
Value in Health Regional Issues,
1(1), 7-14. https://doi.org/10.1016/j.vhri.2012.03.007
Tu,
H. A., de Vries, R., Woerdenbag, H., Li, SC., Le, H.,
Phan, TL., van Hulst, M., & Postma,
M. (2012). Cost-effectiveness of hepatitis B
immunization in Vietnam: application of affordability curves in
decision making. Value in Health,
(Regional issue) (1), 7-14.
Tu,
H. A. T., Woerdenbag, H. J., Riewpaiboon, A., Kane,
S., Le, D. M., Postma, M. J., & Li, S. C. (2012).
Cost of Illness of Chronic Hepatitis B Infection in
Vietnam. Value in Health Regional
Issues, 1(1), 23-28. https://doi.org/10.1016/j.vhri.2012.03.008
Tu,
H., Riewpaiboon , A., Woerdenbag, H., Le, H., Le, MD.,
Phan, TL., Postma, M., & Li, SC. (2012).
Cost-of-illness of chronic hepatitis B in Vietnam.
Value in Health, 1( (Regional Issue)
), 23-28.
Bakker,
P., Woerdenbag, H., Gooskens, V., Naafs, B.,
Kaaij, R. V. D., & Wieringa, N. (2012).
Dermatological preparations for the tropics. A formulary
of dermatological preparations and background information on
choices, production and dispensing. s.n.
Tu,
H.-A. T., Rozenbaum, M. H., Coyte, P. C., Li, S. C.,
Woerdenbag, H. J., & Postma, M. J. (2012).
Health economics of rotavirus immunization in Vietnam:
Potentials for favorable cost-effectiveness in developing
countries. Vaccine, 30(8),
1521-1528. https://doi.org/10.1016/j.vaccine.2011.11.052
Hendrawati,
O., Hille, J., Woerdenbag, H. J.,
Quax, W. J., & Kayser, O. (2012). In vitro
regeneration of wild chervil (Anthriscus sylvestris L.).
In vitro cellular & developmental
biology-Plant, 48(3), 355-361. https://doi.org/10.1007/s11627-011-9410-3
Hendrawati,
O., Woerdenbag, H. J., Hille, J., &
Kayser, O. (2012). Metabolic Engineering of Medicinal Plants
and Microorganisms for the Production of Natural Products.
In O. Kayser, & H. Warzecha (Eds.), Pharmaceutical
Biotechnology: Drug Discovery and Clinical Applications, Second
Edition (pp. 491-526). s.n..
Woerdenbag,
H. J., Nguyen, T. M., Vu, D. V., Tran, H.,
Nguyen, D. T., Tran, T. V., De Smet, P. A., & Brouwers, J. R.
(2012). Vietnamese traditional medicine from a pharmacist's
perspective. Expert Review of Clinical
Pharmacology, 5(4), 459-477. https://doi.org/10.1586/ecp.12.34
2011
Hendrawati,
O., Hille, J., Woerdenbag, H. J., Warzecha, H.,
Dekker, F. J., Quax, W. J., & Kayser, O.
(2011). Agrobacterium mediated transformation of Anthriscus
sylvestris with human cytochrome P450 3A4 followed by
regeneration. In Studies on Anthriscus sylvestris L.
(HOFFM.): Metabolic engineering of combinatorial biosynthesis of
podophyllotoxin (pp. 93-106)
Schellekens,
R. C. A., Stellaard, F., Woerdenbag, H. J.,
Frijlink, H. W., & Kosterink, J. G. W.
(2011). Applications of stable isotopes in clinical
pharmacology. British Journal of Clinical
Pharmacology, 72(6), 879-897. https://doi.org/10.1111/j.1365-2125.2011.04071.x
Tu,
H. A. T., Woerdenbag, H. J., Kane, S., Rozenbaum, M.
H., Li, S. C., & Postma, M. J. (2011).
Economic evaluations of rotavirus immunization for developing
countries: a review of the literature. Expert
review of vaccines, 10(7), 1037-1051. https://doi.org/10.1586/ERV.11.65
Woerdenbag,
H. J., Dillingh, J. H., Wanders, J. T. M., Boer, E.
J., Frijlink, H. W., Kosterink, J. G. W.,
& Schellekens, R. C. A. (2011). Elastomeer-infuuspompen
getest voor de praktijk. Pharmaceutisch
Weekblad, 146(15), 58-64.
Hendrawati,
O., Woerdenbag, H. J., Michiels, P. J. A., Aantjes, H.
G., van Dam, A., & Kayser, O. (2011). Identification of
lignans and related compounds in Anthriscus sylvestris by
LC-ESI-MS/MS and LC-SPE-NMR.
Phytochemistry, 72(17), 2172-2179.
https://doi.org/10.1016/j.phytochem.2011.08.009
Hendrawati,
O., Woerdenbag, H. J., Hille, J.,
Quax, W. J., & Kayser, O. (2011). Seasonal
Variations in the Deoxypodophyllotoxin Content and Yield of
Anthriscus sylvestris L. (Hoffm.) Grown in the Field and under
Controlled Conditions. Journal of Agricultural and
Food Chemistry, 59(15), 8132-8139. https://doi.org/10.1021/jf200177q
2010
Staniek,
A., Muntendam, R., Woerdenbag, H. J., & Kayser, O.
(2010). Essential oil constituents derived from different
organs of a relictual conifer Wollemia nobilis.
Biochemical Systematics and Ecology,
38(2), 131-135. https://doi.org/10.1016/j.bse.2009.12.022
Schellekens,
R. C. A., Baltink, J. H., Woesthuis, E. M., Stellaard, F.,
Kosterink, J. G. W., Woerdenbag, H. J.,
& Frijlink, H. W. (2010). Film coated tablets
(ColoPulse technology) for targeted delivery in the lower
intestinal tract: influence of the core composition on release
characteristics. Pharmaceutical development and
technology, 17(1), 40-47. https://doi.org/10.3109/10837450.2010.513986
Hendrawati,
O., Woerdenbag, H. J., Hille, J., &
Kayser, O. (2010). Metabolic engineering strategies for the
optimization of medicinal and aromatic plants: realities and
expectations. Zeitschrift für Arznei- &
Gewurzpflanzen, 15(3), 111-126.
Schellekens,
R. C. A., Stellaard, F., Olsder, G. G., Woerdenbag, H.
J., Frijlink, H. W., & Kosterink, J.
G. W. (2010). Oral ileocolonic drug delivery by the
colopulse-system: A bioavailability study in healthy
volunteers. Journal of controlled release :
official journal of the Controlled Release Society,
146(3), 334-340. https://doi.org/10.1016/j.jconrel.2010.05.028
Ruslan
Wirasutisna, K., Batterman, S., Koulman, A., Kayser, O.,
Woerdenbag, H. J., & Quax, W. J. (2010).
Reduced Coniferin and Enhanced 6-Methoxypodophyllotoxin
Production in Linum flavum Cell Cultures.
Pharmacognosy Journal, 2(17), 74-80.
https://doi.org/10.1016/S0975-3575(10)80015-X
Tu,
H. A. T., Bos, J. H. J., Woerdenbag, H.
J., Visser, S. T., Wilschut, J. C., van Assen,
S., de Jong-van den Berg, L. T. W., & Postma, M.
J. (2010). Results of a retrospective database
analysis of drug utilization and costs for treatment of chronic
hepatitis B virus infection in the northern Netherlands between
2000 and 2006. Clinical Therapeutics,
32(1), 133-144. https://doi.org/10.1016/j.clinthera.2010.01.015
Staniek,
A., Woerdenbag, H. J., & Kayser, O. (2010).
Screening the endophytic flora of Wollemia nobilis for
alternative paclitaxel sources. Journal of plant
interactions, 5(3), 189-195. https://doi.org/10.1080/17429141003714721
2009
Aslan,
S., Kartal, M., Kurucu, S., Kuiper, J. M., Kruizinga, W. H., Bos,
R., Woerdenbag, H. J., & Kayser, O. (2009).
Composition of the Essential Oil From Roots and Rhizomes of
Valeriana phu L. Growing Wild in Turkey. Journal
of Essential Oil Research, 21(5),
437-440.
Tu,
H. A. T., Woerdenbag, H. J., Kane, S., Riewpaiboon,
A., van Hulst, M., & Postma, M. J.
(2009). Economic evaluations of hepatitis B vaccination for
developing countries. Expert review of
vaccines, 8(7), 907-920. https://doi.org/10.1586/ERV.09.53
Azizi,
M., Davareenejad, G., Woerdenbag, H. J., & Kayser,
O. (2009). Essential oil content and constituents of black
zira [bunium persicum [boiss.] b. fedtsch.) from iran during field
cultivation (domestication). Journal of Essential
Oil Research, 21(3), 193-194. https://doi.org/10.1080/10412905.2009.9700145
Azizi,
M., Davareenejad, G., Bos, R., Woerdenbag, H. J.,
& Kayser, O. (2009). Essential Oil Content and
Constituents of Black Zira (Bunium persicum [Boiss.] B. Fedtsch.)
from Iran During Field Cultivation (Domestication).
Journal of Essential Oil Research,
21(1), 78-82.
| Last modified: | 09 June 2023 8.36 p.m. |